[HTML][HTML] The management of portal hypertension: rational basis, available treatments and future options

J Bosch, A Berzigotti, JC Garcia-Pagan… - Journal of hepatology, 2008 - Elsevier
Variceal bleeding is the last step in a chain of events initiated by an increase in portal
pressure, followed by the development and progressive dilation of varices until these finally …

Current management of portal hypertension

J Bosch, JG Abraldes… - Journal of hepatology, 2003 - journal-of-hepatology.eu
The management of portal hypertension should be based on an updated knowledge of its
natural history. Portal hypertension is an almost unavoidable complication of cirrhosis, and it …

Early use of TIPS in patients with cirrhosis and variceal bleeding

JC García-Pagán, K Caca, C Bureau… - … England Journal of …, 2010 - Mass Medical Soc
Background Patients with cirrhosis in Child–Pugh class C or those in class B who have
persistent bleeding at endoscopy are at high risk for treatment failure and a poor prognosis …

[BOOK][B] Hepatology Principles and Practice: History· Morphology Biochemistry· Diagnostics Clinic· Therapy

E Kuntz - 2006 - Springer
Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

[PDF][PDF] Lack of difference among terlipressin, somatostatin, and octreotide in the control of acute gastroesophageal variceal hemorrhage

YS Seo, SY Park, MY Kim, JH Kim, JY Park… - …, 2014 - Wiley Online Library
Vasoactive drugs are recommended to be started as soon as possible in suspected variceal
bleeding, even before diagnostic endoscopy. However, it is still unclear whether the …

Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy

JG Abraldes, C Villanueva, R Bañares, C Aracil… - Journal of …, 2008 - Elsevier
BACKGROUND/AIMS: In acute variceal bleeding (AVB) hepatic venous pressure gradient
(HVPG) is associated with prognosis. However, this has not been studied in patients …

[PDF][PDF] Portal hypertension and variceal bleeding—Unresolved issues. Summary of an American Association for the study of liver diseases and European Association …

G Garcia‐Tsao, J Bosch, RJ Groszmann - Hepatology, 2008 - Wiley Online Library
Many randomized controlled trials (RCTs) have advanced the knowledge of the
complications of portal hypertension, specifically in the management of varices and variceal …

A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleeding

C Villanueva, M Piqueras, C Aracil, C Gómez… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: The currently recommended treatment for acute variceal bleeding is
the association of vasoactive drugs and endoscopic therapy. However, which emergency …

Emergency sclerotherapy versus vasoactive drugs for variceal bleeding in cirrhosis: a Cochrane meta-analysis

G D'Amico, G Pietrosi, I Tarantino, L Pagliaro - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: Emergency sclerotherapy is used as a first-line therapy for variceal
bleeding in cirrhosis, although pharmacologic treatment stops bleeding in most patients. We …

Portal hypertension and gastrointestinal bleeding

J Bosch, JG Abraldes, A Berzigotti… - Seminars in liver …, 2008 - thieme-connect.com
Variceal bleeding is one of the most serious complications of portal hypertension. The
driving force for the development of varices is an increase in portal pressure. As portal …