Robotic micromanipulation is a relatively young field. However, after three decades of
development and evolution, the fundamental physics; techniques for sensing, actuation, and …

Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

The capability to directly interrogate intracellular structures inside a single cell for
measurement and manipulation is important for understanding subcellular and suborganelle …

Aims Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right
ventricular myocardial replacement and life-threatening ventricular arrhythmias …

Thanks to the advancements in micro-and nanomechatronics techniques, the capability to
inject foreign materials into target locations inside biosamples has become increasingly …

In cell biology, fluorescent dyes are routinely used for biochemical measurements. The
traditional global dye treatment method suffers from low signal-to-noise ratios (SNR) …

Microengineering/nanoengineering is an emerging field that enables engineering and
scientific discoveries in the microworld. As an effective and powerful tool for automation and …

This paper presents the design and development of a piezo-driven cell injection system with
the fusion of force and position control. By integrating a polyvinylidene fluoride force sensor …

Detecting and segmenting unstained living adherent cells in differential interference contrast
(DIC) images is crucial in biomedical research, such as cell microinjection, cell tracking, cell …

This paper presents the design of a novel flexure-based precision positioning stage with
constant output force for biological cell micromanipulation. One uniqueness of the proposed …