The inositol trisphosphate/calcium signaling pathway in health and disease

MJ Berridge - Physiological reviews, 2016 - journals.physiology.org
Many cellular functions are regulated by calcium (Ca2+) signals that are generated by
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …

Abnormal calcium handling in Duchenne muscular dystrophy: mechanisms and potential therapies

S Mareedu, ED Million, D Duan, GJ Babu - Frontiers in physiology, 2021 - frontiersin.org
Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …

Ion channels of the sarcolemma and intracellular organelles in Duchenne muscular dystrophy: a role in the dysregulation of ion homeostasis and a possible target for …

MV Dubinin, KN Belosludtsev - International Journal of Molecular …, 2023 - mdpi.com
Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …

Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell–derived skeletal muscle in vitro

Z Al Tanoury, JF Zimmerman, J Rao… - Proceedings of the …, 2021 - National Acad Sciences
Duchenne muscular dystrophy (DMD) is a devastating genetic disease leading to
degeneration of skeletal muscles and premature death. How dystrophin absence leads to …

PAX7, a key for myogenesis modulation in muscular dystrophies through multiple signaling pathways: a systematic review

NIA Rahman, CL Lam, N Sulaiman… - International Journal of …, 2023 - mdpi.com
Muscular dystrophy is a heterogenous group of hereditary muscle disorders caused by
mutations in the genes responsible for muscle development, and is generally defined by a …

Bioenergetic and metabolic impairments in induced pluripotent stem cell-derived cardiomyocytes generated from Duchenne muscular dystrophy patients

L Willi, I Abramovich, J Fernandez-Garcia… - International journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene and
dilated cardiomyopathy (DCM) is a major cause of morbidity and mortality in DMD patients …

A Review of the Role of Endo/Sarcoplasmic Reticulum-Mitochondria Ca2+ Transport in Diseases and Skeletal Muscle Function

SS Zhang, S Zhou, ZJ Crowley-McHattan… - International journal of …, 2021 - mdpi.com
The physical contact site between a mitochondrion and endoplasmic reticulum (ER), named
the mitochondria-associated membrane (MAM), has emerged as a fundamental platform for …

[HTML][HTML] IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice

D Valladares, Y Utreras-Mendoza, C Campos… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Duchenne muscular dystrophy (DMD) is characterized by a severe and progressive
destruction of muscle fibers associated with altered Ca 2+ homeostasis. We have previously …

Genome-wide analysis reveals extensive changes in LncRNAs during skeletal muscle development in Hu sheep

C Ren, M Deng, Y Fan, H Yang, G Zhang, X Feng, F Li… - Genes, 2017 - mdpi.com
As an important type of noncoding RNA molecules, long non-coding RNAs (lncRNAs) act as
versatile players in various biological processes. However, little is known about lncRNA …

Skeletal ryanodine receptors are involved in impaired myogenic differentiation in Duchenne muscular dystrophy patients

P Meyer, C Notarnicola, AC Meli, S Matecki… - International Journal of …, 2021 - mdpi.com
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle wasting
following repeated muscle damage and inadequate regeneration. Impaired myogenesis and …