Synthesis of sulfur-containing heterocycles via ring enlargement

BF Abdel-Wahab, S Shaaban, GA El-Hiti - Molecular Diversity, 2018 - Springer
The current review deals with the use of ring expansion reactions for the synthesis of sulfur-
containing heterocycles. Ring enlargement offers by far a convenient method for the …

NBS-Promoted Synthesis of Thiocyanated Aminomaleimides and Site-Selective Intramolecular Cyclization Access to 1, 4-Benzothiazepines via S–CN Bond Cleavage

Q Yang, S Huang, L Yin, Z Wang, X Chen… - The Journal of Organic …, 2024 - ACS Publications
A transition metal-free concise and efficient protocol for the synthesis of thiocyanated
aminomaleimides and benzo [e][1, 4] thiazepine derivatives has been developed. The …

Synthesis of novel [3, 1]-benzothiazepine and [3, 1]-benzoxazepine derivatives with antitumoral activity

WR Martínez, GCG Militao, TG da Silva, RO Silva… - RSC Advances, 2014 - pubs.rsc.org
A new method for the synthesis of [3, 1]-benzothiazepines and [3, 1]-benzoxazepines from
the reaction of C-allylanilines and isothiocyanates or isocyanates without the need for the …

Expected and unexpected reactions of 1, 3-benzothiazine derivatives, I. Ring transformation of β-lactam-condensed 1, 3-benzothiazines into 4, 5-dihydro-1, 4 …

L Fodor, P Csomós, T Holczbauer, A Kálmán… - Tetrahedron …, 2011 - Elsevier
The ring-enlargement reactions of monochloro-β-lactam-fused 2-aryl-1, 3-benzothiazines
revealed that the reactions of ortho-nitro aryl-substituted derivatives with sodium methoxide …

Synthesis of 1, 3-thiazines by a three-component reaction and their transformations into β-lactam-condensed 1, 3-thiazine and 1, 4-thiazepine derivatives

F Peudru, JF Lohier, M Gulea… - Phosphorus, Sulfur, and …, 2016 - Taylor & Francis
ABSTRACT Variously substituted 1, 3-thiazines have been prepared by a three-component
reaction involving a thioamide, an aldehyde, and an alkene. Two diastereomeric thiazines …

Stereoselective synthesis of novel monocyclic trans-3-halogenated-4-pyrazolyl-β-lactams: Potential synthons and promising biologically active agents

S Berry, SS Bari, BK Banik, A Bhalla - Synthetic Communications, 2017 - Taylor & Francis
Stereoselective synthesis of novel monocyclic trans-3-halogenated-4-pyrazolyl-β-lactams 5
is described. The reaction of ketene derived from α-bromo/chloroethanoic acids 4 using …

Expected and unexpected reactions of 1, 3-benzothiazine derivatives, II. Formation of isomeric 5, 6-dihydro-1, 5-benzothiazocines

L Fodor, P Csomós, A Csámpai, P Sohár… - Tetrahedron …, 2011 - Elsevier
A method for the synthesis of medium-sized 1, 5-benzothiazocines by ring enlargement of 1,
3-benzothiazines has been developed. When N-alkyl-1, 3-benzothiazines were reacted with …

Ring transformations of β-lactam-condensed 1, 3-benzothiazines to isoquinoline and thiazole derivatives by sulfur extrusion and addition sequences

L Fodor, P Csomos, A Csámpai, P Sohár - Tetrahedron, 2012 - Elsevier
The ring transformations of dichloro-β-lactam-fused 2-aryl-1, 3-benzothiazines with sodium
methoxide were investigated. With 2 equiv of base, the dichloro-β-lactam derivatives …