Approximately 20 of the 30 mammalian transient receptor potential (TRP) channel subunits
are expressed by specific neurons and cells within the alimentary canal. They subserve …

Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), a well-known vanilloid, which
is the main spicy component in chili peppers, showing several biological activities and the …

Tumour innervation is associated with worse patient outcomes in multiple cancers,, which
suggests that it may regulate metastasis. Here we observed that highly metastatic mouse …

Satiation for food comprises the physiological processes that result in the termination of
eating. Satiation is evoked by physical and chemical qualities of ingested food, which trigger …

The cloning of the vanilloid receptor 1 opened a floodgate for discoveries regarding the
function of this complex molecule. It has been found that, in addition to heat, protons and …

Capsaicin is a phytochemical derived from plants of the genus Capsicum and subject of
intensive phytochemical research due to its numerous physiological and therapeutical …

Purpose: Capsaicin, a constituent of green and red peppers, has been linked with
suppression of tumorigenesis through a mechanism that is not well understood. Because the …

α2-Adrenergic receptors (α2-ARs) mediate a number of physiological phenomena, including
spinal analgesia. We have developed subtype-selective antisera against the C termini of the …

The transient receptor potential vanilloid‐1 (TRPV1) cation channel is a receptor that is
activated by heat (> 42° C), acidosis (pH< 6) and a variety of chemicals among which …

Capsicum annuum L., commonly known as chili pepper, is used as an important spice
globally and as a crude drug in many traditional medicine systems. The fruits of C. annuum …