Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives

N Vaou, E Stavropoulou, C Voidarou, C Tsigalou… - Microorganisms, 2021 - mdpi.com
The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery

U Anand, N Jacobo-Herrera, A Altemimi, N Lakhssassi - Metabolites, 2019 - mdpi.com
The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's
economy. Antibiotics, the bedrock, and wonder drug of the 20th century have played a …

Predicting disease occurrence with high accuracy based on soil macroecological patterns of Fusarium wilt

J Yuan, T Wen, H Zhang, M Zhao, CR Penton… - The ISME …, 2020 - academic.oup.com
Soil-borne plant diseases are increasingly causing devastating losses in agricultural
production. The development of a more refined model for disease prediction can aid in …

Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Marketed marine natural products in the pharmaceutical and cosmeceutical industries: Tips for success

A Martins, H Vieira, H Gaspar, S Santos - Marine drugs, 2014 - mdpi.com
The marine environment harbors a number of macro and micro organisms that have
developed unique metabolic abilities to ensure their survival in diverse and hostile habitats …

Antibiotic discovery: combatting bacterial resistance in cells and in biofilm communities

A Penesyan, M Gillings, IT Paulsen - Molecules, 2015 - mdpi.com
Bacterial resistance is a rapidly escalating threat to public health as our arsenal of effective
antibiotics dwindles. Therefore, there is an urgent need for new antibiotics. Drug discovery …

Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases

S Lordan, RP Ross, C Stanton - Marine drugs, 2011 - mdpi.com
The marine environment represents a relatively untapped source of functional ingredients
that can be applied to various aspects of food processing, storage, and fortification …

Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?

J Hubert, JM Nuzillard, JH Renault - Phytochemistry Reviews, 2017 - Springer
The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …

Chemical interactions between marine macroalgae and bacteria

F Goecke, A Labes, J Wiese, JF Imhoff - Marine ecology progress series, 2010 - int-res.com
We review research from the last 40 yr on macroalgal–bacterial interactions. Marine
macroalgae have been challenged throughout their evolution by microorganisms and have …

Concepts and methods to access novel antibiotics from actinomycetes

JJ Hug, CD Bader, M Remškar, K Cirnski, R Müller - Antibiotics, 2018 - mdpi.com
Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …