Reversible phosphorylation of proteins, controlled by kinases and phosphatases, is involved
in various cellular processes. Dual-specificity phosphatases (DUSPs) can dephosphorylate …

Recently, fibroblast growth factors are identified to play a vital role in the development and
progression of human pancreatic cancer. FGF pathway is critical involved in numerous …

Oral squamous cell carcinoma (OSCC) is a prevalent form of malignant tumor, characterized
by a persistently high incidence and mortality rate. The extracellular matrix (ECM) plays a …

Background We have previously reported the functional anti-cancer effects of the products of
enzymatic hydrolysis of Citrus unshiu peel (εCUP) and fermented extraction of Citrus unshiu …

Platelet‑derived growth factor (PDGF) is a potent mitogen and chemoattractant that serves a
role in the development of several types of solid cancer, and abnormal PDGF activity has …

Background Cholangiocarcinoma is a devastating cancer with a poor prognosis. Previous
reports have presented conflicting results on the role of transforming growth factor-β-induced …

Platelets have been recognized as key players in hemostasis, thrombosis, and cancer.
Preclinical and clinical researches evidenced that tumorigenesis and metastasis can be …

Contact-based pericellular interactions play important roles in cancer progression via
juxtacrine signaling pathways. The present study revealed that hypoxia-inducible factor-1α …

Platelet-derived growth factor A (PDGFA), the most known member of PDGF family, plays a
crucial role in occurrence and progression of different tumors. However, PDGFA expression …

Background/Aim: The aim of this study was to investigate matrix metalloproteinase 11
(MMP11) as a promising biomarker in human pancreatic cancer. Materials and Methods: A …