Over the last three decades, our understanding of the molecular changes associated with
cancer development and progression has advanced greatly. This has led to new cancer …

Molecular imaging is a rapidly growing new discipline in gastrointestinal endoscopy. It uses
the molecular signature of cells for minimally-invasive, targeted imaging of gastrointestinal …

BACKGROUND & AIMS: Epidermal growth factor receptor (EGFR) is a therapeutic target for
colorectal cancer (CRC). However, technical challenges have limited in vivo imaging of …

Purpose: To develop and validate an optical imaging nanoprobe for the discrimination of
epidermal growth factor (EGF) receptor (EGFR)–overexpressing tumors from surrounding …

Tumor receptors play an important role in carcinogenesis and tumor growth and have been
some of the earliest targets for tumor-specific therapy, for example, the estrogen receptor in …

Oral carcinogenesis proceeds through a stepwise accumulation of genetic damage over
time. Because the oral cavity is easy to examine and risk factors for oral cancer are known …

Oral cancer is the sixth most common cancer worldwide and has been marked by high
morbidity and poor survival rates that have changed little over the past few decades. Beyond …

The human epidermal growth factor receptor (HER) family of receptor tyrosine kinases
controls critical pathways involved in epithelial cell differentiation, growth, division, and …

The emerging tools of in vivo molecular imaging are enabling dynamic cellular and
molecular analyses of disease mechanisms in living animal models and humans. These …

Abstract Purpose: To determine whether Cy5. 5‐labeled antiepidermal growth factor (EGFR)
antibody could be used to detect head and neck squamous cell carcinoma (HNSCC) …