Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Paraquat (PQ) is a cheap and an effective herbicide, which is widely being used worldwide
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …

The brain-and body-first models of Lewy body disorders predict that aggregated alpha-
synuclein pathology usually begins in either the olfactory system or the enteric nervous …

Idiopathic Parkinson's disease (PD) is epidemiologically linked with exposure to toxicants
such as pesticides and solvents, which comprise a wide array of chemicals that pollute our …

The increasing global burden of Parkinson's disease (PD), termed the PD pandemic, is
exceeding expectations related purely to population aging and is likely driven in part by …

Parkinson's disease (PD) is a neurodegenerative disorder with a complex etiology and
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …

Gene-environment interaction is implicated in the majority of idiopathic Parkinson's disease
(PD) risk, and some of the most widespread environmental contaminants are selectively …

Parkinson's disease (PD) is the second most common neurodegenerative disorder with an
unclear etiology and no disease-modifying treatment to date. PD is considered a …

Although sex, genetics, and exposures can individually influence risk for sporadic
Parkinson's disease (PD), the joint contributions of these factors to the epigenetic etiology of …

LRRK2 is a Ser/Thr kinase with multiple functional domains. Studies have shown that
LRRK2 mutations are closely related to hereditary Parkinson's disease. However, its role in …