[HTML][HTML] Machine learning for biochemical engineering: A review

M Mowbray, T Savage, C Wu, Z Song, BA Cho… - Biochemical …, 2021 - Elsevier
The field of machine learning is comprised of techniques, which have proven powerful
approaches to knowledge discovery and construction of 'digital twins' in the highly …

Machine learning in bioprocess development: from promise to practice

LM Helleckes, J Hemmerich, W Wiechert… - Trends in …, 2023 - cell.com
Fostered by novel analytical techniques, digitalization, and automation, modern bioprocess
development provides large amounts of heterogeneous experimental data, containing …

Bioprocess control: current progress and future perspectives

AS Rathore, S Mishra, S Nikita, P Priyanka - Life, 2021 - mdpi.com
Typical bioprocess comprises of different unit operations wherein a near optimal
environment is required for cells to grow, divide, and synthesize the desired product …

Hybrid physics‐based and data‐driven modeling for bioprocess online simulation and optimization

D Zhang, EA Del Rio‐Chanona… - Biotechnology and …, 2019 - Wiley Online Library
Abstract Model‐based online optimization has not been widely applied to bioprocesses due
to the challenges of modeling complex biological behaviors, low‐quality industrial …

Enhancement of isoprene production in engineered Synechococcus elongatus UTEX 2973 by metabolic pathway inhibition and machine learning-based optimization …

I Yadav, A Rautela, A Gangwar, L Wagadre… - Bioresource …, 2023 - Elsevier
An engineered Synechococcus elongatus UTEX 2973-IspS. IDI is used to enhance isoprene
production through geranyl diphosphate synthase (CrtE) inhibition and process parameters …

Deep learning‐based surrogate modeling and optimization for microalgal biofuel production and photobioreactor design

EA del Rio‐Chanona, JL Wagner, H Ali… - AIChE …, 2019 - Wiley Online Library
Identifying optimal photobioreactor configurations and process operating conditions is
critical to industrialize microalgae‐derived biorenewables. Traditionally, this was addressed …

[HTML][HTML] Harnessing the potential of artificial neural networks for predicting protein glycosylation

P Kotidis, C Kontoravdi - Metabolic engineering communications, 2020 - Elsevier
Kinetic models offer incomparable insight on cellular mechanisms controlling protein
glycosylation. However, their ability to reproduce site-specific glycoform distributions …

A transfer learning approach for predictive modeling of bioprocesses using small data

AW Rogers, F Vega‐Ramon, J Yan… - Biotechnology and …, 2022 - Wiley Online Library
Predictive modeling of new biochemical systems with small data is a great challenge. To fill
this gap, transfer learning, a subdomain of machine learning that serves to transfer …

When bioprocess engineering meets machine learning: A survey from the perspective of automated bioprocess development

N Duong-Trung, S Born, JW Kim… - Biochemical …, 2023 - Elsevier
Abstract Machine learning (ML) is becoming increasingly crucial in many fields of
engineering but has not yet played out its full potential in bioprocess engineering. While …

Optimization of non-catalytic transesterification of microalgae oil to biodiesel under supercritical methanol condition

G Srivastava, AK Paul, VV Goud - Energy Conversion and Management, 2018 - Elsevier
The present study aims to maximize the conversion of microalgae oil to fatty acid methyl
ester (FAME) using supercritical methanol (SCM) transesterification by sequential hybrid …