The effects of childhood maltreatment on brain structure, function and connectivity
Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …
illness and substance abuse. Although the association between maltreatment and …
Annual research review: enduring neurobiological effects of childhood abuse and neglect
Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …
psychopathology accounting for about 45% of the population attributable risk for childhood …
Recognizing the importance of childhood maltreatment as a critical factor in psychiatric diagnoses, treatment, research, prevention, and education
Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …
Effects of stress throughout the lifespan on the brain, behaviour and cognition
SJ Lupien, BS McEwen, MR Gunnar… - Nature reviews …, 2009 - nature.com
Chronic exposure to stress hormones, whether it occurs during the prenatal period, infancy,
childhood, adolescence, adulthood or aging, has an impact on brain structures involved in …
childhood, adolescence, adulthood or aging, has an impact on brain structures involved in …
[CITATION][C] Why people die by suicide
TE Joiner - Harvard University Pres, 2005 - books.google.com
In the wake of a suicide, the most troubling questions are invariably the most difficult to
answer: How could we have known? What could we have done? And always, unremittingly …
answer: How could we have known? What could we have done? And always, unremittingly …
The enduring effects of abuse and related adverse experiences in childhood: A convergence of evidence from neurobiology and epidemiology
Background Childhood maltreatment has been linked to a variety of changes in brain
structure and function and stress–responsive neurobiological systems. Epidemiological …
structure and function and stress–responsive neurobiological systems. Epidemiological …
The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …
stage of development can have long-lasting consequences. It is associated with a marked …
Adverse childhood experiences, allostasis, allostatic load, and age-related disease
A Danese, BS McEwen - Physiology & behavior, 2012 - Elsevier
How do adverse childhood experiences get 'under the skin'and influence health outcomes
through the life-course? Research reviewed here suggests that adverse childhood …
through the life-course? Research reviewed here suggests that adverse childhood …
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …
Adverse childhood experiences and the consequences on neurobiological, psychosocial, and somatic conditions across the lifespan
JI Herzog, C Schmahl - Frontiers in psychiatry, 2018 - frontiersin.org
Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …
neglect are frequent in childhood and constitute a massive stressor with long-lasting …