DOE optimization of nano-based carrier of pregabalin as hydrogel: New therapeutic & chemometric approaches for controlled drug delivery systems

MG Arafa, BM Ayoub - Scientific reports, 2017 - nature.com
Niosomes entrap** pregabalin (PG) were prepared using span 60 and cholesterol in
different molar ratios by hydration method, the remaining PG from the hydrating solution was …

Nanosized ethosomal dispersions for enhanced transdermal delivery of nebivolol using intradermal/transfollicular sustained reservoir: in vitro evaluation, confocal laser …

SA Fouad, ST Khatab, MH Teaima… - Pharmaceutical …, 2024 - Taylor & Francis
Nebivolol (NBV), a BCS class II anti-hypertensive drug, suffers from limited solubility and
oral bioavailability. Nanosized ethosomes were adopted as an approach to solubilize and …

Development and evaluation of tofacitinib transdermal system for the treatment of rheumatoid arthritis in rats

Y Li, Y Sun, S Wei, L Zhang, S Zong - Drug Development and …, 2021 - Taylor & Francis
Context Tofacitinib tablet is approved for the treatment of rheumatoid arthritis (RA). However,
tofacitinib (Tfc) faces extensive first-pass metabolism following oral administration. Aim To …

[PDF][PDF] Design, development, and evaluation of transdermal patches containing memantine hydrochloride

SK Valeveti, S Pashikanti - International Journal of Applied …, 2023 - academia.edu
Objective: This study aimed to develop an effective transdermal drug delivery system of
memantine hydrochloride (MH), an anti-Alzheimer's drug, to improve patient compliance and …

[PDF][PDF] Formulation and evaluation of transdermal patches containing dexketoprofen trometamol

D Trivedi, A Goyal - Int. J. Pharm. Chem. Anal, 2020 - researchgate.net
Dexketoprofen Trometamol is a NSAID, used as an analgesic and anti-inflammatory drug. It
works by blocking the action of cyclo-oxygenase in the body. Conventional route of delivery …

Design and characterisation of rosuvastatin calcium nanosuspension loaded transdermal patch

D Joshi, M Tiwari, B Singh… - Letters in Drug Design & …, 2023 - benthamdirect.com
Objective: The present investigation highlights the formulation and evaluation of
nanosuspension-loaded transdermal patches of poorly soluble antilipidemic drug …

Fabrication, optimization, and evaluation of transdermal patch: as an alternative and effective transdermal delivery system for nebivolol HCl

AS Patil, S Birkodi, RS Masareddy… - Pharmaceutical …, 2024 - benthamdirect.com
Background: Nebivolol HCl is a unique third-generation beta blocker that has less oral
bioavailability and exhibits various adverse effects like gastrointestinal disturbance and …

[PDF][PDF] Formulasi Nanoemulsi Ekstrak Terpurifikasi Daun Afrika (Vernonia amygdalina) Terinkoporasi dalam Dissolved Microneedle Patch

A Daryati, MT Suryaningrum, A Prakoso, I Ramandhita… - J Pharm Sci, 2022 - academia.edu
Sistem penghantaran sediaan patch transdermal mampu meningkatkan kepatuhan pasien,
diabetes melitus dengan menghindari regimen dosis yang rumit serta penggunaan injeksi …

Transdermal patch, co-loaded with Pregabalin and Ketoprofen for improved bioavailability; in vitro studies

N Shafique, T Siddiqui, M Zaman… - Polymers and …, 2021 - journals.sagepub.com
The current study was aimed to fabricate a transdermal drug delivery system (TDDS)
containing Ketoprofen (KTF) and Pregabalin (PGB) for controlled drug release, avoidance of …

[PDF][PDF] Formulation and evaluation of baclofen mucoadhesive buccal films

MAM Ali, AM Sabati, BA Ali - FABAD Journal of Pharmaceutical …, 2017 - researchgate.net
Aim of the present work was to formulate and design mucoadhesive buccal films of baclofen
(muscle relaxant) using different hydrophilic polymers and to evaluate them. The baclofen …