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Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
The use of RNA-based treatments in the field of cancer immunotherapy
M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release
J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024 - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …
accomplish their biological functions, which limits their biomedical applications …
Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization
T Ye, Z Jiao, X Li, Z He, Y Li, F Yang, X Zhao, Y Wang… - Nature, 2023 - nature.com
The COVID-19 pandemic has fostered major advances in vaccination technologies,,–;
however, there are urgent needs for vaccines that induce mucosal immune responses and …
however, there are urgent needs for vaccines that induce mucosal immune responses and …
Bioinspired and biomimetic delivery platforms for cancer vaccines
Cancer vaccines aim at eliciting tumor‐specific responses for the immune system to identify
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …
Exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases
H Bao, Y Tian, H Wang, T Ye, S Wang, J Zhao… - Nature Biomedical …, 2024 - nature.com
The therapeutic benefits of many cell types involve paracrine mechanisms. Inspired by the
paracrine functions of exosomes and the sustained degradation properties of …
paracrine functions of exosomes and the sustained degradation properties of …
Hyperbaric oxygen enhances tumor penetration and accumulation of engineered bacteria for synergistic photothermal immunotherapy
Bacteria-mediated cancer therapeutic strategies have attracted increasing interest due to
their intrinsic tumor tropism. However, bacteria-based drugs face several challenges …
their intrinsic tumor tropism. However, bacteria-based drugs face several challenges …
Polymeric nanoparticle-based nanovaccines for cancer immunotherapy
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
The Development of Chiral Nanoparticles to Target NK Cells and CD8+ T Cells for Cancer Immunotherapy
The chirality of nanomaterials (nanoparticles, NPs) can influence their interaction with cells
and biological systems. However, how chirality can exert impact on the immune response …
and biological systems. However, how chirality can exert impact on the immune response …
Antibody-based drug delivery systems for cancer therapy: Mechanisms, challenges, and prospects
In recent years, antibody-based cancer therapy has emerged as one of the efficient
therapeutic strategies, such as immune checkpoint inhibitors (ICIs), angiogenesis inhibitors …
therapeutic strategies, such as immune checkpoint inhibitors (ICIs), angiogenesis inhibitors …