The diversity of venom: the importance of behavior and venom system morphology in understanding its ecology and evolution

V Schendel, LD Rash, RA Jenner, EAB Undheim - Toxins, 2019‏ - mdpi.com
Venoms are one of the most convergent of animal traits known, and encompass a much
greater taxonomic and functional diversity than is commonly appreciated. This knowledge …

Sea anemones: Quiet achievers in the field of peptide toxins

P J. Prentis, A Pavasovic, R S. Norton - Toxins, 2018‏ - mdpi.com
Sea anemones have been understudied as a source of peptide and protein toxins, with
relatively few examined as a source of new pharmacological tools or therapeutic leads. This …

Diversity analysis of sea anemone peptide toxins in different tissues of Heteractis crispa based on transcriptomics

Q Guo, J Fu, L Yuan, Y Liao, M Li, X Li, B Yi, J Zhang… - Scientific Reports, 2024‏ - nature.com
Peptide toxins found in sea anemones venom have diverse properties that make them
important research subjects in the fields of pharmacology, neuroscience and biotechnology …

Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery

SD Robinson, EAB Undheim… - Expert review of …, 2017‏ - Taylor & Francis
Introduction: Animal venoms are complex chemical arsenals. Most venoms are rich in
bioactive peptides with proven potential as research tools, drug leads and drugs. Areas …

Sea anemone venom: Ecological interactions and bioactive potential

C Menezes, NL Thakur - Toxicon, 2022‏ - Elsevier
This article provides a brief overview of the literature related to the chemical ecology of sea
anemones, focusing on their venom, and summarizing their bioprospecting potential. Sea …

Revisiting venom of the sea anemone Stichodactyla haddoni: Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

B Madio, EAB Undheim, GF King - Journal of Proteomics, 2017‏ - Elsevier
More than a century of research on sea anemone venoms has shown that they contain a
diversity of biologically active proteins and peptides. However, recent omics studies have …

Tissue-specific venom composition and differential gene expression in sea anemones

J Macrander, M Broe, M Daly - Genome biology and evolution, 2016‏ - academic.oup.com
Cnidarians represent one of the few groups of venomous animals that lack a centralized
venom transmission system. Instead, they are equipped with stinging capsules collectively …

Ecological venomics: How genomics, transcriptomics and proteomics can shed new light on the ecology and evolution of venom

K Sunagar, D Morgenstern, AM Reitzel, Y Moran - Journal of Proteomics, 2016‏ - Elsevier
Animal venom is a complex cocktail of bioactive chemicals that traditionally drew interest
mostly from biochemists and pharmacologists. However, in recent years the evolutionary …

Multiomic Approach for Bioprospection: Investigation of Toxins and Peptides of Brazilian Sea Anemone Bunodosoma caissarum

ME Mazzi Esquinca, CN Correa, G Marques de Barros… - Marine Drugs, 2023‏ - mdpi.com
Sea anemones are sessile invertebrates of the phylum Cnidaria and their survival and
evolutive success are highly related to the ability to produce and quickly inoculate venom …

A process of convergent amplification and tissue‐specific expression dominates the evolution of toxin and toxin‐like genes in sea anemones

JM Surm, HL Smith, B Madio, EAB Undheim… - Molecular …, 2019‏ - Wiley Online Library
Members of phylum Cnidaria are an ancient group of venomous animals and rely on a
number of specialized tissues to produce toxins in order to fulfil a range of ecological roles …