Biological mediators of insect immunity

JP Gillespie and, MR Kanost… - Annual review of …, 1997 - annualreviews.org
▪ Abstract Infection in insects stimulates a complex defensive response. Recognition of
pathogens may be accomplished by plasma or hemocyte proteins that bind specifically to …

Estimating disease resistance in insects: phenoloxidase and lysozyme-like activity and disease resistance in the cricket Gryllus texensis

SA Adamo - Journal of insect physiology, 2004 - Elsevier
An animal's ability to resist disease is usually estimated by measuring one or more
components of the immune system. There is an assumption that these assays of immunity …

Subunit composition of pro-phenol oxidase from Manduca sexta: molecular cloning of subunit ProPO-P1

H Jiang, Y Wang, C Ma, MR Kanost - Insect biochemistry and molecular …, 1997 - Elsevier
Phenol oxidase (PO) is known to play an important role in defense mechanisms in insect
immunity. It is present as a zymogen in insect hemolymph, and can be activated by a specific …

The role of the gut in insect chilling injury: cold-induced disruption of osmoregulation in the fall field cricket, Gryllus pennsylvanicus

HA MacMillan, BJ Sinclair - Journal of Experimental Biology, 2011 - journals.biologists.com
To predict the effects of changing climates on insect distribution and abundance, a clear
understanding of the mechanisms that underlie critical thermal limits is required. In insects …

Purification, characterization and molecular cloning of prophenoloxidases from Sarcophaga bullata

MR Chase, K Raina, J Bruno, M Sugumaran - Insect Biochemistry and …, 2000 - Elsevier
Prophenoloxidase (PPO) is a key enzyme associated with both melanin biosynthesis and
sclerotization in insects. This enzyme is involved in three physiologically important …

Phenoloxidase activity in Apis mellifera honey bee pupae, and ecdysteroid-dependent expression of the prophenoloxidase mRNA

MS Zufelato, AP Lourenço, ZLP Simões… - Insect biochemistry and …, 2004 - Elsevier
Phenoloxidase (monophenol, l-dopa: oxygen oxidoreductase, EC 1.14. 18.1) is a
multicopper oxidase, which plays an important role in melanin synthesis, necessary for …

Phenoloxidase in larvae of Plodia interpunctella (Lepidoptera: Pyralidae): Molecular cloning of the proenzyme cDNA and enzyme activity in larvae paralyzed and parasitized by …

KL Hartzer, KY Zhu, JE Baker - Archives of Insect Biochemistry …, 2005 - Wiley Online Library
Phenoloxidase (PO) is a major component of the insect immune system. The enzyme is
involved in encapsulation and melanization processes as well as wound healing and cuticle …

Purification and characterization of hemolymph prophenoloxidase from Ostrinia furnacalis (Lepidoptera: Pyralidae) larvae

C Feng, Q Song, W Lü, J Lu - … and Physiology Part B: Biochemistry and …, 2008 - Elsevier
Prophenoloxidase (PPO) was isolated from the hemolymph of Ostrinia furnacalis larvae and
purified to homogeneity. A 369.85-fold purification and 35.34% recovery of activity were …

Molecular characterization of a prophenoloxidase cDNA from the malaria mosquito Anopheles stephensi

L Cui, S Luckhart, R Rosenberg - Insect molecular biology, 2000 - Wiley Online Library
Some refractory anopheline mosquitoes are capable of killing Plasmodium, the causative
agent of malaria, by melanotic encapsulation of invading ookinetes. Phenoloxidase (PO) …

Control mechanisms of the prophenoloxidase cascade

M Sugumaran - Phylogenetic Perspectives on the Vertebrate Immune …, 2001 - Springer
Insects do not possess innnunoglobulins and other complicated immune proteins found in
higher animals. However, they are equipped with a highly effective defense arsenal to …