Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy

DI Ellis, R Goodacre - Analyst, 2006 - pubs.rsc.org
The ability to diagnose the early onset of disease, rapidly, non-invasively and unequivocally
has multiple benefits. These include the early intervention of therapeutic strategies leading …

Diffuse optical imaging using spatially and temporally modulated light

TD O'Sullivan, AE Cerussi, DJ Cuccia… - … of biomedical optics, 2012 - spiedigitallibrary.org
The authors describe the development of diffuse optical imaging (DOI) technologies,
specifically the use of spatial and temporal modulation to control near infrared light …

Metabolic fingerprinting as a diagnostic tool

DI Ellis, WB Dunn, JL Griffin, JW Allwood… - …, 2007 - Taylor & Francis
Within the framework of systems biology, functional analyses at all 'omic levels have seen an
intense level of activity during the first decade of the twenty-first century. These include …

In vivo absorption, scattering, and physiologic properties of 58 malignant breast tumors determined by broadband diffuse optical spectroscopy

A Cerussi, N Shah, D Hsiang, A Durkin… - … of biomedical optics, 2006 - spiedigitallibrary.org
Diffuse optical imaging (DOI) may be a beneficial diagnostic method for women with
mammographically dense breast tissue. In order to evaluate the utility of DOI, we are …

Lighting up tumors with receptor-specific optical molecular probes

S Achilefu - Technology in cancer research & treatment, 2004 - journals.sagepub.com
Accurate and rapid detection of tumors is of great importance for interrogating the molecular
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …

Bulk optical properties of healthy female breast tissue

T Durduran, R Choe, JP Culver, L Zubkov… - Physics in medicine …, 2002 - iopscience.iop.org
We have measured the bulk optical properties of healthy female breast tissues in vivo in the
parallel plate, transmission geometry. Fifty-two volunteers were measured. Blood volume …

Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy

A Cerussi, D Hsiang, N Shah… - Proceedings of the …, 2007 - National Acad Sciences
Diffuse optical spectroscopy (DOS) and imaging are emerging diagnostic techniques that
quantitatively measure the concentration of deoxy-hemoglobin (ctHHb), oxy-hemoglobin …

Diffuse optical imaging of the healthy and diseased breast: a systematic review

DR Leff, OJ Warren, LC Enfield, A Gibson… - Breast cancer research …, 2008 - Springer
Screening X-ray mammography is limited by false positives and negatives leading to
unnecessary physical and psychological morbidity. Diffuse Optical Imaging using harmless …

Interpreting hemoglobin and water concentration, oxygen saturation, and scattering measured in vivo by near-infrared breast tomography

S Srinivasan, BW Pogue, S Jiang… - Proceedings of the …, 2003 - National Acad Sciences
Near-infrared spectroscopic tomography was used to measure the properties of 24
mammographically normal breasts to quantify whole-breast absorption and scattering …

Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy

BJ Tromberg, A Cerussi, N Shah, M Compton… - Breast Cancer …, 2005 - Springer
Diffuse optical spectroscopy (DOS) and diffuse optical imaging (DOI) are non-invasive
diagnostic techniques that employ near-infrared (NIR) light to quantitatively characterize the …