Large animal models in regenerative medicine and tissue engineering: to do or not to do
I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …
increasing drive toward clinical translation of breakthrough technologies. However, the …
Equine asthma: current understanding and future directions
The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the
latest information on Equine Asthma and provide future research directions. Current clinical …
latest information on Equine Asthma and provide future research directions. Current clinical …
Inflammatory airway disease of horses—revised consensus statement
The purpose of this manuscript is to revise and update the previous consensus statement on
inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific …
inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific …
Equine asthma: Integrative biologic relevance of a recently proposed nomenclature
The term “equine asthma” has been proposed as a unifying descriptor of inflammatory
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …
Asthma: the use of animal models and their translational utility
Asthma is characterized by chronic lower airway inflammation that results in airway
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …
Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease
YS Prakash - American Journal of Physiology-Lung Cellular …, 2016 - journals.physiology.org
Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …
aging, as well as of lung responses to the environment and the pathophysiology of important …
The contribution of oxidative stress and inflamm-aging in human and equine asthma
Aging is associated with a dysregulation of the immune system, leading to a general pro-
inflammatory state of the organism, a process that has been named inflamm-aging …
inflammatory state of the organism, a process that has been named inflamm-aging …
An official American Thoracic Society research statement: current challenges facing research and therapeutic advances in airway remodeling
Background: Airway remodeling (AR) is a prominent feature of asthma and other obstructive
lung diseases that is minimally affected by current treatments. The goals of this Official …
lung diseases that is minimally affected by current treatments. The goals of this Official …
Lipid species profiling of bronchoalveolar lavage fluid cells of horses housed on two different bedding materials
J Mönki, M Holopainen, H Ruhanen, N Karikoski… - Scientific reports, 2023 - nature.com
The lipidome of equine BALF cells has not been described. The objectives of this
prospective repeated-measures study were to explore the BALF cells' lipidome in horses …
prospective repeated-measures study were to explore the BALF cells' lipidome in horses …
Fatty acid fingerprints in bronchoalveolar lavage fluid and its extracellular vesicles reflect equine asthma severity
N Höglund, P Nieminen, AM Mustonen, R Käkelä… - Scientific reports, 2023 - nature.com
Equine asthma (EA) is an inflammatory disease of the lower airways driven by mediators
released from cells. Extracellular vesicles (EVs) are vehicles for lipid mediators, which …
released from cells. Extracellular vesicles (EVs) are vehicles for lipid mediators, which …