Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Trait-associated genetic variants affect complex phenotypes primarily via regulatory
mechanisms on the transcriptome. To investigate the genetics of gene expression, we …
mechanisms on the transcriptome. To investigate the genetics of gene expression, we …
Strategies to annotate and characterize long noncoding RNAs: advantages and pitfalls
The past decade has seen an explosion of interest in long noncoding RNAs (lncRNAs).
However, despite the massive volume of scientific data implicating these transcripts in a …
However, despite the massive volume of scientific data implicating these transcripts in a …
An integrated expression atlas of miRNAs and their promoters in human and mouse
MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As
part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) …
part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) …
An atlas of human long non-coding RNAs with accurate 5′ ends
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally
uncharacterized. Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we …
uncharacterized. Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we …
Update of the FANTOM web resource: expansion to provide additional transcriptome atlases
M Lizio, I Abugessaisa, S Noguchi, A Kondo… - Nucleic acids …, 2019 - academic.oup.com
The FANTOM web resource (http://fantom. gsc. riken. jp/) was developed to provide easy
access to the data produced by the FANTOM project. It contains the most complete and …
access to the data produced by the FANTOM project. It contains the most complete and …
FANTOM5 CAGE profiles of human and mouse samples
S Noguchi, T Arakawa, S Fukuda, M Furuno… - Scientific data, 2017 - nature.com
In the FANTOM5 project, transcription initiation events across the human and mouse
genomes were mapped at a single base-pair resolution and their frequencies were …
genomes were mapped at a single base-pair resolution and their frequencies were …
FANTOM enters 20th year: expansion of transcriptomic atlases and functional annotation of non-coding RNAs
Abstract The Functional ANnoTation Of the Mammalian genome (FANTOM) Consortium has
continued to provide extensive resources in the pursuit of understanding the transcriptome …
continued to provide extensive resources in the pursuit of understanding the transcriptome …
Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta
Haematopoietic stem cells (HSCs) are generated from haemogenic endothelial (HE) cells
via the formation of intra-aortic haematopoietic clusters (IAHCs) in vertebrate embryos. The …
via the formation of intra-aortic haematopoietic clusters (IAHCs) in vertebrate embryos. The …
[HTML][HTML] refTSS: a reference data set for human and mouse transcription start sites
I Abugessaisa, S Noguchi, A Hasegawa… - Journal of molecular …, 2019 - Elsevier
Transcription starts at genomic positions called transcription start sites (TSSs), producing
RNAs, and is mainly regulated by genomic elements and transcription factors binding …
RNAs, and is mainly regulated by genomic elements and transcription factors binding …
[HTML][HTML] Long noncoding RNA study: Genome-wide approaches
Long noncoding RNAs (lncRNAs) have been confirmed to play a crucial role in various
biological processes across several species. Though many efforts have been devoted to the …
biological processes across several species. Though many efforts have been devoted to the …