The expression of Ki67 is strongly associated with tumor cell proliferation and growth, and is
widely used in routine pathological investigation as a proliferation marker. The nuclear …

In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …

DNA has many physical and chemical properties that make it a powerful material for
molecular constructions at the nanometer length scale. In particular, its ability to form …

Over the last four decades nucleic acid hybridization techniques have been widely used for
the detection of specific nucleic acid sequences. In this approach a 15-nucleotide or longer …

Recently, programmable assembly technologies have enabled the application of DNA in the
creation of new nanomaterials with unprecedented functionality. One of the most common …

Oligonucleotide gene therapy (OGT) agents (eg antisense, deoxyribozymes, siRNA and
CRISPR/Cas) are promising therapeutic tools. Despite extensive efforts, only few OGT drugs …

Electronic Bio Sciences, San Diego, CA, USA. Planar lipid bilayer (PLB) apparatus provide
an excellent platform for the study of isolated membrane proteins. The noise performance …

Sensing nucleic acid sequences is critical in modern-day biology and medicine, and is likely
to continue to increase in importance over the next 10r20 years. The current uses for …

Conspectus Hybridization probes are RNA or DNA oligonucleotides or their analogs that
bind to specific nucleotide sequences in targeted nucleic acids (analytes) via Watson–Crick …

Peptide nucleic acid (PNA) is a nucleobase oligomer in which the entire backbone has been
replaced by a backbone composed of N‐(2‐aminoethyl) glycine units. In other words, PNA …