Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

[LIVRE][B] Solid-state nanopore sensors for nucleic acid analysis

BM Venkatesan, R Bashir - 2011 - Springer
Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

FraC nanopores with adjustable diameter identify the mass of opposite-charge peptides with 44 dalton resolution

G Huang, A Voet, G Maglia - Nature communications, 2019 - nature.com
A high throughput single-molecule method for identifying peptides and sequencing proteins
based on nanopores could reduce costs and increase speeds of sequencing, allow the …

Discrimination of oligonucleotides of different lengths with a wild-type aerolysin nanopore

C Cao, YL Ying, ZL Hu, DF Liao, H Tian… - Nature …, 2016 - nature.com
Protein nanopores offer an inexpensive, label-free method of analysing single
oligonucleotides. The sensitivity of the approach is largely determined by the characteristics …

Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores

G Huang, K Willems, M Soskine, C Wloka… - Nature …, 2017 - nature.com
Biological nanopores are nanoscale sensors employed for high-throughput, low-cost, and
long read-length DNA sequencing applications. The analysis and sequencing of proteins …

Nanopore sensors for biomolecular characterization

R Bashir, BM Venkatesan - US Patent 10,175,195, 2019 - Google Patents
Provided herein are methods and devices for characterizing a biomolecule parameter by a
nanopore-containing mem brane, and also methods for making devices that can be used in …

Solid-state and biological nanopore for real-time sensing of single chemical and sequencing of DNA

F Haque, J Li, HC Wu, XJ Liang, P Guo - Nano today, 2013 - Elsevier
Sensitivity and specificity are two most important factors to take into account for molecule
sensing, chemical detection and disease diagnosis. A perfect sensitivity is to reach the level …

Multistep protein unfolding during nanopore translocation

D Rodriguez-Larrea, H Bayley - Nature nanotechnology, 2013 - nature.com
Cells are divided into compartments and separated from the environment by lipid bilayer
membranes. Essential molecules are transported back and forth across the membranes. We …

Nanopore‐based sequencing and detection of nucleic acids

YL Ying, J Zhang, R Gao… - Angewandte Chemie …, 2013 - Wiley Online Library
Nanopore‐based techniques, which mimic the functions of natural ion channels, have
attracted increasing attention as unique methods for single‐molecule detection. The …

Modeling and simulation of ion channels

C Maffeo, S Bhattacharya, J Yoo, D Wells… - Chemical …, 2012 - ACS Publications
Transport of ions through pores in membranes is a process of fundamental importance to
cell biology. In living organisms, such transport is facilitated by ion channels that utilize the …