Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Nanoarchitectured structure and surface biofunctionality of mesoporous silica nanoparticles

RK Kankala, YH Han, J Na, CH Lee, Z Sun… - Advanced …, 2020 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs), one of the important porous materials, have
garnered interest owing to their highly attractive physicochemical features and …

[HTML][HTML] Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

C Duan, M Yu, J Xu, BY Li, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

[HTML][HTML] Therapeutic applications of selenium nanoparticles

A Khurana, S Tekula, MA Saifi, P Venkatesh… - Biomedicine & …, 2019 - Elsevier
Nanoparticles (NPs) serve to reduce the toxicity, enhance bioactivity, improve targeting, and
provide versatile means to control the release profile of the encapsulated moiety. Among …

Current perspectives and trend of nanomedicine in cancer: A review and bibliometric analysis

Z Pei, S Chen, L Ding, J Liu, X Cui, F Li, F Qiu - Journal of Controlled …, 2022 - Elsevier
The limitations of traditional cancer treatments are driving the creation and development of
new nanomedicines. At present, with the rapid increase of research on nanomedicine in the …

Nanotechnology for multimodal synergistic cancer therapy

W Fan, B Yung, P Huang, X Chen - Chemical reviews, 2017 - ACS Publications
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …

Active targeting of gold nanoparticles as cancer therapeutics

ZR Goddard, MJ Marín, DA Russell… - Chemical Society …, 2020 - pubs.rsc.org
Gold nanoparticles (AuNPs) are of increasing interest for their unique properties and their
biocompatability, minimal toxicity, multivalency and size tunability make them exciting drug …

[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics

S Zhao, X Yu, Y Qian, W Chen, J Shen - Theranostics, 2020 - ncbi.nlm.nih.gov
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …

Development of high‐drug‐loading nanoparticles

Y Liu, G Yang, S **, L Xu, CX Zhao - ChemPlusChem, 2020 - Wiley Online Library
Formulating drugs into nanoparticles offers many attractive advantages over free drugs
including improved bioavailability, minimized toxic side effects, enhanced drug delivery …