Affordable drug resistance genoty** of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings

S Manyana, M Pillay, L Gounder, A Khan… - AIDS Research and …, 2023 - Springer
Background As use of dolutegravir (DTG) becomes more common in resource limited
settings (RLS), the demand for integrase resistance testing is increasing. Affordable …

HIV-1 subtype diversity and factors affecting drug resistance among patients with virologic failure in antiretroviral therapy in Hainan province, China, 2014–2020

YU De E, YJ Xu, LI Mu, Y Yuan, HY Liang… - Biomedical and …, 2023 - Elsevier
Objective This study aimed to determine the HIV-1 subtype distribution and HIV drug
resistance (HIVDR) in patients with ART failure from 2014 to 2020 in Hainan, China …

Exploring disparities in HIV-1 pretreatment and acquired drug resistance in China from 2003 to 2022

Z Wang, H Jiang, X Pang, J Li, S Liang… - Journal of …, 2024 - academic.oup.com
Objectives To investigate the epidemic patterns of pretreatment drug resistance (PDR) and
acquired drug resistance (ADR) in HIV-1 sequences from China. Methods HIV-1 pol …

[HTML][HTML] Patterns of HIV-1 Drug Resistance Observed Through Geospatial Analysis of Routine Diagnostic Testing in KwaZulu-Natal, South Africa

L Gounder, A Khan, J Manasa, R Lessells, A Tomita… - Viruses, 2024 - mdpi.com
HIV-1 drug resistance (HIVDR) impedes treatment and control of HIV-1, especially in high-
prevalence settings such as KwaZulu-Natal (KZN) province, South Africa. This study merged …

Geospatial and temporal map** of detectable HIV-1 viral loads amid dolutegravir rollout in KwaZulu-Natal, South Africa

L Gounder, A Tomita, R Lessells… - PLOS Global Public …, 2024 - journals.plos.org
South Africa rolled out dolutegravir (DTG) as first-line antiretroviral therapy (ART) in
December 2019 to overcome high rates of pretreatment non-nucleoside reverse …

Brief communication: The rate of switching from first-line to second-line antiretroviral therapy among people living with HIV in Aden City, Yemen

NM Al-Haidary, EA Radman - AIDS Research and Therapy, 2024 - Springer
Background Effective management of antiretroviral therapy (ART) is crucial in combating the
global HIV pandemic. This study, the first of its kind in Yemen, investigates the rate and …

Virological, weight, and drug resistance outcomes among patients initiating a dolutegravir-based first line ART regimen in Zimbabwe

V Kouamou, T Washaya, T Mapangisana, CE Ndhlovu… - AIDS, 2022 - journals.lww.com
Objective: Dolutegravir (DTG)-based ART is being scaled up in Africa. However, clinical
experience with DTG and patterns of HIV drug resistance (HIVDR) are sparse in Zimbabwe …

Prevalence, predictors and geospatial patterns of HIV drug resistance in South Africa: Insights from the 2017 national HIV household survey

M Seleka, N Ledibane, T Mokhele, K Zuma, S Moyo… - 2024 - researchsquare.com
Background South Africa bears the highest HIV burden globally, marked by a substantial
expansion of antiretroviral therapy (ART) that curbs HIV and AIDS cases, morbidity, and …

Validation of a Low-cost in-house Hiv Integrase Inhibitor Drug-resistance Assay and Characterization of the Pol-Integrase Region From Patients Failing Treatment at …

VM Onwonga - 2022 - erepository.uonbi.ac.ke
Background: HIV drug resistance testing (DRT) plays an essential role in the surveillance of
HIV drug resistance (HIVDR) and informs on the effectiveness of treatment regimens for …

[引用][C] Innovative and affordable HIV-1 drug resistance testing for resource limited settings.

SC Manyana - 2022