Recalibrating the relevance of adult neurogenesis

JS Snyder - Trends in neurosciences, 2019 - cell.com
Conflicting reports about whether adult hippocampal neurogenesis occurs in humans raise
questions about its significance for human health and the relevance of animal models …

Integrated treatment of substance use and psychiatric disorders

TM Kelly, DC Daley - Social work in public health, 2013 - Taylor & Francis
Epidemiological studies find that psychiatric disorders, including mental disorders and
substance use disorders, are common among adults and highly comorbid. Integrated …

Adjunctive ketamine with relapse prevention–based psychological therapy in the treatment of alcohol use disorder

M Grabski, A McAndrew, W Lawn… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Early evidence suggests that ketamine may be an effective treatment to sustain
abstinence from alcohol. The authors investigated the safety and efficacy of ketamine …

Neurobiology of addiction

GF Koob, DB Kandel, RD Baler, ND Volkow - Tasman's Psychiatry, 2023 - Springer
Substance use disorders (SUDs) manifest as chronic relapsing disorders, characterized by
compulsive drug taking despite serious adverse consequences, the loss of control over …

[BOOK][B] Addiction and change: How addictions develop and addicted people recover

CC DiClemente - 2018 - books.google.com
Not everyone who experiments with substance use or risky behavior becomes addicted, and
many who are addicted have been able to recover. This authoritative book, now revised and …

[HTML][HTML] Alcohol's effects on the brain: neuroimaging results in humans and animal models

NM Zahr, A Pfefferbaum - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

[HTML][HTML] Adult neurogenesis in humans: a review of basic concepts, history, current research, and clinical implications

A Kumar, V Pareek, MA Faiq, SK Ghosh… - Innovations in clinical …, 2019 - ncbi.nlm.nih.gov
Neurogenesis in adult humans remains a controversial area of research among
neuroscientists. Methodological challenges have hampered investigators from conducting …

Ketamine for the treatment of addiction: evidence and potential mechanisms

II Ezquerra-Romano, W Lawn, E Krupitsky… - …, 2018 - Elsevier
Ketamine is a dissociative anaesthetic drug which acts on the central nervous system chiefly
through antagonism of the n-methyl-d-aspartate (NMDA) receptor. Recently, ketamine has …

Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle

G Gonzalez-Cuevas, R Martin-Fardon… - …, 2018 - nature.com
Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa, has
received attention for therapeutic potential in treating neurologic and psychiatric disorders …

[HTML][HTML] The problem with the current high potency THC marijuana from the perspective of an addiction psychiatrist

E Stuyt - Missouri medicine, 2018 - ncbi.nlm.nih.gov
The active component in marijuana that people find so desirable was not really known until
the 1960s when a research team in Israel found that after injecting THC into aggressive …