Background Respiratory distress, particularly respiratory distress syndrome (RDS), is the
single most important cause of morbidity and mortality in preterm infants. In infants with …

Noninvasive ventilation, a novel treatment to increase alveolar ventilation, is accomplished
with either subatmospheric or positive pressure administered via an external interface. In …

The ethical basis for entering patients in randomised controlled trials is under debate. Some
doctors espouse the uncertainty principle whereby randomisation to treatment is acceptable …

Background Respiratory distress syndrome (RDS) is the single most important cause of
morbidity and mortality in preterm infants. In infants with progressive respiratory …

The use of noninvasive ventilation (NIV)/ventilatory assistance has in its modern form
experienced a resurgence during the last two decades, primarily in the adult population …

Objective: We aimed to compare clinical presentation and risk factors associated with the
development of pneumothorax among newborns of different birth weight (BW) categories …

Negative-pressure ventilation (NPV) was the primary mode of assisted ventilation for
patients with acute respiratory failure until the Copenhagen polio epidemic in the 1950s …

Current methods of obtaining consent for emergency neonatal research are flawed. They
risk aggravating the distress of parents of preterm and other sick neonates. This distress …

Mechanical ventilation of the newborn infant has increased neonatal survival. However, this
increased survival has come at the expense of increased morbidity, in the form of …

In the 3rd century BC Erasistratus of Chios recognised that breathing depended on muscular
action. By 1555 Vesalius had described assisted positive pressure ventilation and in 1667 …