Objective To systematically identify and narratively synthesize the evidence surrounding
liposomal delivery of gene therapy and the outcome for ovarian cancer. Methods An …

The members of the p53 family comprise p53, p63, and p73, and full-length isoforms of the
p53 family have a tumor suppressor function. However, p53, but not p63 or p73, has a high …

Cancer stem cells (CSCs) have an established role in cancer progression and therapeutic
resistance. The p63 proteins are important transcription factors which belong to the p53 …

The p53 family member p63 exists as two major protein variants (TAp63 and ΔNp63) with
distinct expression patterns and functional properties. Whilst downstream target genes of …

The TP63 gene encodes two major protein variants; TAp63 contains a p53-like transcription
domain and consequently has tumor suppressor activities whereas ΔNp63 lacks this domain …

The p53 family of proteins has grown substantially over the last 40 years. It started with p53,
then p63, p73, isoforms and mutants of these proteins. The function of p53 as a tumour …

MicroRNAs (miRNAs) are small RNA molecules that regulate more than 30% of genes in
humans. Recent studies have revealed that miRNAs play a crucial role in tumorigenesis …

Survival mechanisms are activated in tumor cells in response to therapeutic ionizing
radiation. This reduces a treatment's effectiveness. The p53, p63, and p73 proteins …

Ultraviolet (UV) is divided into UVA (long‑wave, 320‑400 nm), UVB (middle‑wave, 280‑320
nm) and UVC (short‑wave, 100‑280 nm) based on wavelength. UV radiation (UVR) from …

Simple Summary It is believed that metal complexes might be interesting alternatives to the
small organic molecules for the treatment of cancer. Due to the variety of metal oxidation …