Probiotics mechanism of action on immune cells and beneficial effects on human health

C Mazziotta, M Tognon, F Martini, E Torreggiani… - Cells, 2023 - mdpi.com
Immune cells and commensal microbes in the human intestine constantly communicate with
and react to each other in a stable environment in order to maintain healthy immune …

[HTML][HTML] Advanced molecular and immunological diagnostic methods to detect SARS-CoV-2 infection

JC Rotondo, F Martini, M Maritati, E Caselli… - Microorganisms, 2022 - mdpi.com
Simple Summary COVID-19 emerged in late 2019 in China and rapidly spread across the
globe. After 2 years, numerous advances have been made. First of all, the preventive …

[HTML][HTML] The role of purinergic P2X7 receptor in inflammation and cancer: novel molecular insights and clinical applications

JC Rotondo, C Mazziotta, C Lanzillotti, C Stefani… - Cancers, 2022 - mdpi.com
Simple Summary The purinergic P2X7 receptor (P2X7R) is a cell membrane protein whose
activation has been related to a variety of cellular processes, while its dysregulation has …

The role of histone post-translational modifications in merkel cell carcinoma

C Mazziotta, C Lanzillotti, R Gafà, A Touzé… - Frontiers in …, 2022 - frontiersin.org
Merkel Cell Carcinoma (MCC) is a rare but highly aggressive form of non–melanoma skin
cancer whose 5-year survival rate is 63%. Merkel cell polyomavirus (MCPyV), a small DNA …

The risk of spontaneous abortion does not increase following first trimester mRNA COVID-19 vaccination

IM Citu, C Citu, F Gorun, I Sas, F Bratosin… - Journal of Clinical …, 2022 - mdpi.com
Clinical trials for COVID-19 vaccines initially excluded pregnant women due to safety
concerns, and when the vaccines were authorized for emergency use, they were not …

Amebic liver abscess by Entamoeba histolytica

D Usuda, S Tsuge, R Sakurai, K Kawai… - World journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Amebic liver abscesses (ALAs) are the most commonly encountered extraintestinal
manifestation of human invasive amebiasis, which results from Entamoeba histolytica (E …

Immortalized erythroid cells as a novel frontier for in vitro blood production: current approaches and potential clinical application

CF Cervellera, C Mazziotta, G Di Mauro… - Stem cell research & …, 2023 - Springer
Background Blood transfusions represent common medical procedures, which provide
essential supportive therapy. However, these procedures are notoriously expensive for …

All‐trans retinoic acid exhibits anti‐proliferative and differentiating activity in Merkel cell carcinoma cells via retinoid pathway modulation

C Mazziotta, G Badiale, CF Cervellera… - Journal of the …, 2024 - Wiley Online Library
Background The limited therapies available for treating Merkel cell carcinoma (MCC), a
highly aggressive skin neoplasm, still pose clinical challenges, and novel treatments are …

Advances in the immunoescape mechanisms exploited by alphaherpesviruses

Y Wang, C Ma, S Wang, H Wu, X Chen, J Ma… - Frontiers in …, 2024 - frontiersin.org
Alphaherpesviruses, categorized as viruses with linear DNA composed of two
complementary strands, can potentially to induce diseases in both humans and animals as …

METTL3 promotes the progression of osteosarcoma through the N6-methyladenosine modification of MCAM via IGF2BP1

D Song, Q Wang, Z Yan, M Su, H Zhang, L Shi, Y Fan… - Biology Direct, 2024 - Springer
Background The molecular mechanisms of osteosarcoma (OS) are complex. In this study,
we focused on the functions of melanoma cell adhesion molecule (MCAM) …