[HTML][HTML] The PI3K/Akt signaling axis in Alzheimer's disease: a valuable target to stimulate or suppress?

E Razani, A Pourbagheri-Sigaroodi… - Cell Stress and …, 2021 - Elsevier
Among the long list of age-related complications, Alzheimer's disease (AD) has the most
dreadful impact on the quality of life due to its devastating effects on memory and cognitive …

Neuregulin-1/ErbB network: An emerging modulator of nervous system injury and repair

H Kataria, A Alizadeh, S Karimi-Abdolrezaee - Progress in neurobiology, 2019 - Elsevier
Abstract Neuregulin-1 (Nrg-1) is a member of the Neuregulin family of growth factors with
essential roles in the develo** and adult nervous system. Six different types of Nrg-1 (Nrg …

Neuronal migration mechanisms in development and disease

M Valiente, O Marín - Current opinion in neurobiology, 2010 - Elsevier
Neuronal migration is a fundamental process that determines the final allocation of neurons
in the nervous system, establishing the basis for the subsequent wiring of neural circuitry …

Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in …

AJ Law, JE Kleinman, DR Weinberger… - Human molecular …, 2007 - academic.oup.com
Abstract The neuregulin 1 (NRG1) receptor, ErbB4, has been identified as a potential risk
gene for schizophrenia. HER4/ErbB4 is a receptor tyrosine kinase whose transcript …

All EGF (ErbB) receptors have preformed homo-and heterodimeric structures in living cells

RH Tao, IN Maruyama - Journal of cell science, 2008 - journals.biologists.com
The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, also known
as ErbB or HER, plays crucial roles in the development of multicellular organisms. Mutations …

Epidermal growth factor receptor–mediated signal transduction in the development and therapy of gliomas

MK Nicholas, RV Lukas, NF Jafri, L Faoro… - Clinical Cancer …, 2006 - aacrjournals.org
The epidermal growth factor receptor (EGFR) and its ligands figure prominently in the
biology of gliomas, the most common tumors of the central nervous system (CNS). Although …

Integrative mechanisms of oriented neuronal migration in the develo** brain

I Evsyukova, C Plestant, ES Anton - Annual review of cell and …, 2013 - annualreviews.org
The emergence of functional neuronal connectivity in the develo** cerebral cortex
depends on neuronal migration. This process enables appropriate positioning of neurons …

Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury

A Alizadeh, S Karimi‐Abdolrezaee - The Journal of physiology, 2016 - Wiley Online Library
Myelin is a proteolipid sheath enwrap** axons in the nervous system that facilitates signal
transduction along the axons. In the central nervous system (CNS), oligodendrocytes are …

[LLIBRE][B] The neurobiology of olfaction

A Menini - 2009 - taylorfrancis.com
Comprehensive Overview of Advances in OlfactionThe common belief is that human smell
perception is much reduced compared with other mammals, so that whatever abilities are …

The role of the phosphatidylinositide 3-kinase–protein kinase B pathway in schizophrenia

HO Kalkman - Pharmacology & therapeutics, 2006 - Elsevier
Neuroanatomical studies of brains from schizophrenic patients report evidence for neuronal
dystrophy, while in genetic studies in schizophrenia there is evidence for mutations in …