NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

A well-functioning immune system is vital for a healthy body. Inadequate and excessive
immune responses underlie diverse pathologies such as serious infections, metastatic …

Asthma is a chronic inflammatory airway disease associated with type 2 cytokines
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …

The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …

Allergic bronchial asthma is a chronic disease of the airways that is characterized by
symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute …

Asthma is a disease of heterogeneous pathology, typically characterised by excessive
inflammatory and bronchoconstrictor responses to the environment. The clinical expression …

We have known for 18 years that people with asthma are at risk of more severe outcomes
with common cold virus infections than are people without asthma (3), and we also know …

Viral respiratory tract infections are associated with asthma inception in early life and asthma
exacerbations in older children and adults. Although how viruses influence asthma inception …

Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous, progressive
inflammatory airway disease associated with a significant impact on patients' lives, including …