In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …

Erythropoietin (EPO) is a glycoprotein that is mainly produced in the adult kidney, and it was
initially highlighted for its action on the hematopoietic system. Moreover, EPO is also …

Periodontitis is an inflammatory disease induced by complex interactions between host
immune system and plaque microorganism. Alveolar bone resorption caused by …

The growth factor erythropoietin (EPO) and erythropoietin receptors (EPOR) are expressed
in the nervous system. Neuronal expression of EPO and EPOR peaks during brain …

Methods A systematic PubMed search up to June 2011 was undertaken to identify
medications with evidence of neuroprotection in pre-clinical studies when given either …

Erythropoietin (EPO), originally discovered as hematopoietic growth factor, has direct effects
on cells of the nervous system that make it a highly attractive candidate drug for …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results
in progressive loss of motoneurons, motor weakness and death within 3–5 years after …

The synthesis of erythropoiesis-stimulating agents (ESAs), especially recombinant human
erythropoietin, has provided a new therapeutic option for the treatment of patients with …

Introduction: The hypoxia-inducible factor (HIF) system mediates the body's response to
hypoxia, locally, inducing angiogenesis and a shift to anaerobic metabolism, and …

Functional whole blood haemostatic assays are used increasingly to guide transfusion
therapy and monitor medical treatment and are also applied for in-vitro evaluations of the …