Bladder cancer is mainly a disease of aging; its incidence and prevalence increase around
the sixth decade and peak in the seventh to eighth decade of life. It is the ninth most …

In 2018, 550,000 people were diagnosed with bladder cancer (BC), of which nearly 200,000
people died. Moreover, men are 4 times more likely than women to be diagnosed with BC …

Context Invasive bladder cancer is a frequently occurring disease with a high mortality rate
despite optimal treatment. The European Association of Urology (EAU) Muscle-invasive and …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Most sequenced genomes are currently stored in strict access-controlled repositories,,. Free
access to these data could improve the power of genome-wide association studies (GWAS) …

We performed a multistage genome-wide association study including 7,683 individuals with
pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome …

Background Genomic regions identified by genome-wide association studies (GWAS) for
bladder cancer risk provide new insights into etiology. Objective To identify new …

Pancreatic cancer is the fourth leading cause of cancer death in the developed world. Both
inherited high-penetrance mutations in BRCA2 (ref.), ATM, PALB2 (ref.), BRCA1 (ref.) …

Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract
and primary cause for hysterectomy, leading to considerable morbidity and high economic …

High rates of APOBEC-signature mutations are found in many tumors, but factors affecting
this mutation pattern are not well understood. Here we explored the contribution of two …