Neurofibromatosis type 1 is a complex autosomal dominant disorder caused by germline
mutations in the NF1 tumour suppressor gene. Nearly all individuals with neurofibromatosis …

The wide variety of clinical manifestations of the genetic syndrome neurofibromatosis type 1
(NF1) are driven by overactivation of the RAS pathway. Mitogen-activated protein kinase …

Employing cellular environment for the self-assembly of supramolecular nanofibers for
biological applications has been widely explored. But using one precursor to differentiate …

Highlights•Pyrophosphate prevents unwanted calcification making it the body's natural
'water-softener'.•The breakdown of ATP released from cells represents a key source of …

Conventional intratumoural drug delivery systems often struggle to achieve both high
permeability and long-term retention. Smaller nanoparticles (NPs) readily diffuse into deep …

Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key
determinant of overall bone formation and bone mass. Despite extensive studies showing …

Attachment of lipid tails to oligonucleotides has emerged as a powerful technology in
constructing cell membrane-anchorable nucleic acid-based probes. In practice, however …

Cancer treatments that combine chemotherapy with immunotherapy are becoming
increasingly effective, but chemotherapy is generally considered to have …

Neurofibromatosis type 1 is the most common neurocutaneous syndrome, with a frequency
of 1 in 2500 persons. Diagnosis is paramount in the pretumor stage to provide proper …

Structurally‐colored photonic hydrogels which are fabricated by introducing hydrogels into
thin films or photonic crystal structures are promising candidates for biosensing. Generally …