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[HTML][HTML] Therapeutic targets in allergic conjunctivitis
Allergic conjunctivitis (AC) is a common condition resulting from exposure to allergens such
as pollen, animal dander, or mold. It is typically mediated by allergen-induced crosslinking of …
as pollen, animal dander, or mold. It is typically mediated by allergen-induced crosslinking of …
Novel anti-fibrotic therapies
BL McVicker, RG Bennett - Frontiers in pharmacology, 2017 - frontiersin.org
Fibrosis is a major player in cardiovascular disease, both as a contributor to the
development of disease, as well as a post-injury response that drives progression. Despite …
development of disease, as well as a post-injury response that drives progression. Despite …
Relaxin as an anti-fibrotic treatment: Perspectives, challenges and future directions
Fibrosis refers to the scarring and hardening of tissues, which results from a failed immune
system-coordinated wound healing response to chronic organ injury and which manifests …
system-coordinated wound healing response to chronic organ injury and which manifests …
Engineered adipose-derived stem cells overexpressing RXFP1 via CRISPR activation ameliorate erectile dysfunction in diabetic rats
Due to the high incidence of diabetes mellitus (DM) and poor response to the first-line
treatment of DM-induced erectile dysfunction (DMED), new therapeutic strategies for DMED …
treatment of DM-induced erectile dysfunction (DMED), new therapeutic strategies for DMED …
Serelaxin enhances the therapeutic effects of human amnion epithelial cell‐derived exosomes in experimental models of lung disease
Background and Purpose There is growing interest in stem cell‐derived exosomes for their
therapeutic and regenerative benefits given their manufacturing and regulatory advantages …
therapeutic and regenerative benefits given their manufacturing and regulatory advantages …
Concise review: fetal membranes in regenerative medicine: new tricks from an old dog?
The clinical application of the fetal membranes dates back to nearly a century. Their use has
ranged from superficial skin dressings to surgical wound closure. The applications of the …
ranged from superficial skin dressings to surgical wound closure. The applications of the …
Mesenchymal Stem/Stromal cells in Asthma Therapy: mechanisms and strategies for enhancement
S Huang, Y Li, J Zeng, N Chang, Y Cheng… - Cell …, 2023 - journals.sagepub.com
Asthma is a complex and heterogeneous disease characterized by chronic airway
inflammation, airway hyperresponsiveness, and airway remodeling. Most asthmatic patients …
inflammation, airway hyperresponsiveness, and airway remodeling. Most asthmatic patients …
Serelaxin as a novel therapeutic opposing fibrosis and contraction in lung diseases
The most common therapies for asthma and other chronic lung diseases are anti-
inflammatory agents and bronchodilators. While these drugs oppose disease symptoms …
inflammatory agents and bronchodilators. While these drugs oppose disease symptoms …
[HTML][HTML] Identification of biomarkers associated with pediatric asthma using machine learning algorithms: A review
K Lin, Y Wang, Y Li, Y Wang - Medicine, 2023 - journals.lww.com
Pediatric asthma is a complex disease with a multifactorial etiology. The identification of
biomarkers associated with pediatric asthma can provide insights into the pathogenesis of …
biomarkers associated with pediatric asthma can provide insights into the pathogenesis of …
iPSC‐and mesenchymoangioblast‐derived mesenchymal stem cells provide greater protection against experimental chronic allergic airways disease compared with …
The airway remodeling (AWR) associated with chronic allergic airways disease
(AAD)/asthma contributes to irreversible airway obstruction. This study compared and …
(AAD)/asthma contributes to irreversible airway obstruction. This study compared and …