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Synthesis, functionalization, and design of magnetic nanoparticles for theranostic applications
J Mosayebi, M Kiyasatfar… - Advanced Healthcare …, 2017 - Wiley Online Library
In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs)
have been presented as a class of non‐invasive nanomaterials for numerous biomedical …
have been presented as a class of non‐invasive nanomaterials for numerous biomedical …
Cell-penetrating peptides to enhance delivery of oligonucleotide-based therapeutics
The promise of nucleic acid based oligonucleotides as effective genetic therapies has been
held back by their low bioavailability and poor cellular uptake to target tissues upon systemic …
held back by their low bioavailability and poor cellular uptake to target tissues upon systemic …
3D printing polymers with supramolecular functionality for biological applications
Supramolecular chemistry continues to experience widespread growth, as fine-tuned
chemical structures lead to well-defined bulk materials. Previous literature described the …
chemical structures lead to well-defined bulk materials. Previous literature described the …
Approaches for evaluation of novel CPP-based cargo delivery systems
Cell penetrating peptides (CPPs) can be broadly defined as relatively short synthetic, protein
derived or chimeric peptides. Their most remarkable property is their ability to cross cell …
derived or chimeric peptides. Their most remarkable property is their ability to cross cell …
Versatility of cell-penetrating peptides for intracellular delivery of siRNA
The plasma membrane is a large barrier to systemic drug delivery into cells, and it limits the
efficacy of drug cargo. This issue has been overcome using cell-penetrating peptides …
efficacy of drug cargo. This issue has been overcome using cell-penetrating peptides …
The formation of nanoparticles between small interfering RNA and amphipathic cell-penetrating peptides
L Pärnaste, P Arukuusk, K Langel, T Tenson… - … Therapy Nucleic Acids, 2017 - cell.com
Cell-penetrating peptides (CPPs) are delivery vectors widely used to aid the transport of
biologically active cargoes to intracellular targets. These cargoes include small interfering …
biologically active cargoes to intracellular targets. These cargoes include small interfering …
Optimization of in vivo DNA delivery with NickFect peptide vectors
As the field of gene therapy progresses, an increasingly urgent need has arisen for efficient
and non-toxic vectors for the in vivo delivery of nucleic acids. Cell-penetrating peptides …
and non-toxic vectors for the in vivo delivery of nucleic acids. Cell-penetrating peptides …
Saturated fatty acid analogues of cell-penetrating peptide PepFect14: role of fatty acid modification in complexation and delivery of splice-correcting oligonucleotides
Modifying cell-penetrating peptides (CPPs) with fatty acids has long been used to improve
peptide-mediated nucleic acid delivery. In this study we have revisited this phenomenon …
peptide-mediated nucleic acid delivery. In this study we have revisited this phenomenon …
[HTML][HTML] Peptide-assisted nucleic acid delivery systems on the rise
S Tarvirdipour, M Skowicki… - International Journal of …, 2021 - mdpi.com
Concerns associated with nanocarriers' therapeutic efficacy and side effects have led to the
development of strategies to advance them into targeted and responsive delivery systems …
development of strategies to advance them into targeted and responsive delivery systems …
Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP
Extracellular synthetic nucleic acids, such as siRNAs, are unable to reach their intended
targets efficiently. Therefore, delivery methods such as cell-penetrating peptides (CPP) …
targets efficiently. Therefore, delivery methods such as cell-penetrating peptides (CPP) …