Learning with Hilbert–Schmidt independence criterion: A review and new perspectives

T Wang, X Dai, Y Liu - Knowledge-based systems, 2021 - Elsevier
Abstract The Hilbert–Schmidt independence criterion (HSIC) was originally designed to
measure the statistical dependence of the distribution-based Hilbert space embedding in …

Sequence representation approaches for sequence-based protein prediction tasks that use deep learning

F Cui, Z Zhang, Q Zou - Briefings in Functional Genomics, 2021 - academic.oup.com
Deep learning has been increasingly used in bioinformatics, especially in sequence-based
protein prediction tasks, as large amounts of biological data are available and deep learning …

MK-FSVM-SVDD: a multiple kernel-based fuzzy SVM model for predicting DNA-binding proteins via support vector data description

Y Zou, H Wu, X Guo, L Peng, Y Ding… - Current …, 2021 - ingentaconnect.com
Background: Detecting DNA-binding proteins (DBPs) based on biological and chemical
methods is time-consuming and expensive. Objective: In recent years, the rise of …

DeepM6ASeq-EL: prediction of human N6-methyladenosine (m6A) sites with LSTM and ensemble learning

J Chen, Q Zou, J Li - Frontiers of Computer Science, 2022 - Springer
Abstract N6-methyladenosine (m 6 A) is a prevalent methylation modification and plays a
vital role in various biological processes, such as metabolism, mRNA processing, synthesis …

sgRNACNN: identifying sgRNA on-target activity in four crops using ensembles of convolutional neural networks

M Niu, Y Lin, Q Zou - Plant molecular biology, 2021 - Springer
Key message We proposed an ensemble convolutional neural network model to identify
sgRNA high on-target activity in four crops and we used one-hot encoding and k-mers for …

CRBPDL: Identification of circRNA-RBP interaction sites using an ensemble neural network approach

M Niu, Q Zou, C Lin - PLoS computational biology, 2022 - journals.plos.org
Circular RNAs (circRNAs) are non-coding RNAs with a special circular structure produced
formed by the reverse splicing mechanism. Increasing evidence shows that circular RNAs …

Identification of sub-Golgi protein localization by use of deep representation learning features

Z Lv, P Wang, Q Zou, Q Jiang - Bioinformatics, 2020 - academic.oup.com
Abstract Motivation The Golgi apparatus has a key functional role in protein biosynthesis
within the eukaryotic cell with malfunction resulting in various neurodegenerative diseases …

A method for identifying vesicle transport proteins based on LibSVM and MRMD

Z Tao, Y Li, Z Teng, Y Zhao - Computational and Mathematical …, 2020 - Wiley Online Library
With the development of computer technology, many machine learning algorithms have
been applied to the field of biology, forming the discipline of bioinformatics. Protein function …

iTTCA-RF: a random forest predictor for tumor T cell antigens

S Jiao, Q Zou, H Guo, L Shi - Journal of translational medicine, 2021 - Springer
Background Cancer is one of the most serious diseases threatening human health. Cancer
immunotherapy represents the most promising treatment strategy due to its high efficacy and …

StackPDB: predicting DNA-binding proteins based on XGB-RFE feature optimization and stacked ensemble classifier

Q Zhang, P Liu, X Wang, Y Zhang, Y Han, B Yu - Applied Soft Computing, 2021 - Elsevier
DNA-binding proteins (DBPs) not only play an important role in all aspects of genetic
activities such as DNA replication, recombination, repair, and modification but also are used …