Engineering tunable catch bonds with DNA
Unlike most adhesive bonds, biological catch bonds strengthen with increased tension. This
characteristic is essential to specific receptor-ligand interactions, underpinning biological …
characteristic is essential to specific receptor-ligand interactions, underpinning biological …
Engineering the Mechanical Stability of a Therapeutic Complex between Affibody and Programmed Death-Ligand 1 by Anchor Point Selection
Protein–protein complexes can vary in mechanical stability depending on the direction from
which force is applied. Here, we investigated the mechanical stability of a complex between …
which force is applied. Here, we investigated the mechanical stability of a complex between …
Engineering the Mechanical Stability of a Therapeutic Affibody/PD-L1 Complex by Anchor Point Selection
B Yang, DEB Gomes, Z Liu, MS Santos, J Li… - …, 2024 - pmc.ncbi.nlm.nih.gov
Protein-protein complexes can vary in mechanical stability depending on the direction from
which force is applied. Here we investigated the anisotropic mechanical stability of a …
which force is applied. Here we investigated the anisotropic mechanical stability of a …
Fine-Tuning of Material Properties via Catch Bonds
Semiflexible polymer networks are ubiquitous in biological systems, including a scaffolding
structure within cells called the actin cytoskeleton. The polymers in these networks are often …
structure within cells called the actin cytoskeleton. The polymers in these networks are often …