Aerosol therapy is a key modality for drug delivery to the lungs of respiratory disease
patients. Aerosol therapy improves therapeutic effects by directly targeting diseased lung …

Background Clinical practice of aerosol delivery in conjunction with respiratory support
devices for critically ill adult patients remains a topic of controversy due to the complexity of …

The delivery of aerosols to mechanically ventilated patients presents unique challenges and
differs from inhaled drug delivery in spontaneously breathing patients in several respects …

BACKGROUND: There has been a growing trend toward delivering aerosolized medications
using high-flow nasal cannula (HFNC). In some cases, patients who do not require high-flow …

BACKGROUND: The aim of this work was to determine the effect of fill volume and
humidification change on aerosol delivery during single-limb noninvasive ventilation (NIV) …

Despite the fact that the nasal-cannula is more comfortable than facemask, using facemask
with high flow oxygen therapy (HFOT) may be beneficial in mouth-breathers. The aim of the …

BACKGROUND: Predosing patients with COPD with salbutamol by using a pressurized
metered-dose-inhaler (pMDI) as a bronchodilator was hypothesized to improve the …

Background During mechanical ventilation medical aerosol delivery has been reported to be
upto two fold greater with dry inhaled gas than with heated humidity. Urine levels at 0.5 h …

Background Patient receiving invasive mechanical ventilation (IMV) may benefit from
medical aerosol, but guidance on dosing with different aerosol devices is limited to in-vitro …

Backgrounds Substituting nebulisers by another, especially in non-invasive ventilation (NIV),
involves many process-variables, eg nebulizer-type and fill-volume of respirable-dose …