Digital histopathology by infrared spectroscopic imaging
R Bhargava - Annual Review of Analytical Chemistry, 2023 - annualreviews.org
Infrared (IR) spectroscopic imaging records spatially resolved molecular vibrational spectra,
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
Infrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging
Chemical imaging, especially mid-infrared spectroscopic microscopy, enables label-free
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …
Laser Direct Infrared Spectroscopy: A cutting-edge approach to microplastic detection in environmental samples
PJI Chandran, S Veerasingam - Talanta, 2024 - Elsevier
Microplastic pollution has emerged as a significant global environmental concern, affecting
marine, terrestrial, and atmospheric ecosystems. As microplastic contamination continues to …
marine, terrestrial, and atmospheric ecosystems. As microplastic contamination continues to …
Resolution limit in infrared chemical imaging
Chemical imaging combines the spatial specificity of optical microscopy with the spectral
selectivity of vibrational spectroscopy. Mid-infrared (IR) absorption imaging instruments are …
selectivity of vibrational spectroscopy. Mid-infrared (IR) absorption imaging instruments are …
Label-Free Monitoring of Coculture System Dynamics: Probing Probiotic and Cancer Cell Interactions via Infrared Spectroscopic Imaging
Evaluating the dynamic interaction of microorganisms and mammalian cells is challenging
due to the lack of suitable platforms for examining interspecies interactions in biologically …
due to the lack of suitable platforms for examining interspecies interactions in biologically …
Phasor Representation Approach for Rapid Exploratory Analysis of Large Infrared Spectroscopic Imaging Data Sets
SS Mukherjee, R Bhargava - Analytical Chemistry, 2023 - ACS Publications
Infrared (IR) spectroscopic imaging is potentially useful for digital histopathology as it
provides spatially resolved molecular absorption spectra, which can subsequently yield …
provides spatially resolved molecular absorption spectra, which can subsequently yield …
On the limit of detection in infrared spectroscopic imaging
Infrared (IR) spectroscopic imaging instruments' performance can be characterized and
optimized by an analysis of their limit of detection (LOD). Here we report a systematic …
optimized by an analysis of their limit of detection (LOD). Here we report a systematic …
Benchtop IR Imaging of Live Cells: Monitoring the Total Mass of Biomolecules in Single Cells
Absolute quantity imaging of biomolecules on a single cell level is critical for measurement
assurance in biosciences and bioindustries. While infrared (IR) transmission microscopy is a …
assurance in biosciences and bioindustries. While infrared (IR) transmission microscopy is a …
Cell Phase Identification in a Three-Dimensional Engineered Tumor Model by Infrared Spectroscopic Imaging
Cell cycle progression plays a vital role in regulating proliferation, metabolism, and
apoptosis. Three-dimensional (3D) cell cultures have emerged as an important class of in …
apoptosis. Three-dimensional (3D) cell cultures have emerged as an important class of in …
Millisecond-resolved infrared spectroscopy study of polymer brush swelling dynamics
We present the study of millisecond-resolved polymer brush swelling dynamics using
infrared spectroscopy with a custom-built quantum cascade laser-based infrared …
infrared spectroscopy with a custom-built quantum cascade laser-based infrared …