The Chinese hamster ovary (CHO) cell line is a well-established platform for the production
of biopharmaceuticals due to its ability to express complex therapeutic proteins with human …

Lycopene represents one of the central compounds in the carotenoid pathway and it exhibits
a potent antioxidant ability with wide potential applications in medicine, food, and cosmetics …

Food shortages due to population growth and climate change are expected to occur in the
near future as a problem that urgently requires solutions. Conventional breeding techniques …

Discovery of genomic safe harbor sites (SHSs) is fundamental for multiple transgene
integrations, such as reporter genes, chimeric antigen receptors (CARs), and safety …

Genome editing has become an important aspect of Chinese hamster ovary (CHO) cell line
engineering for improving the production of recombinant protein therapeutics. Currently, the …

CRISPR Cpf1/Cas12a has been discussed as a less conflict prone alternative, patent-wise,
to Cas9. This article investigates whether or not this assumption is correct, and comes to the …

Snakebite envenoming is a neglected tropical disease that is treated with antivenom based
on polyclonal antibodies derived from the plasma of hyperimmunized animals, such as …

The initial goal of this project was to investigate different production methods for
recombinant adeno-associated virus (rAAV), with a special emphasisonChinese hamster …

Genome editing has become an important aspect of Chinese hamster ovary (CHO) cell line
engineering for improving the production of recombinant protein therapeutics. Currently, the …