Revisiting hematopoiesis: applications of the bulk and single-cell transcriptomics dissecting transcriptional heterogeneity in hematopoietic stem cells
Hematopoietic system (HS) is one of the most unique, adaptive and comprehensive
developmental systems on which various other body systems relies on. It consists of a …
developmental systems on which various other body systems relies on. It consists of a …
Bacterial polyphosphates interfere with the innate host defense to infection
J Roewe, G Stavrides, M Strueve, A Sharma… - Nature …, 2020 - nature.com
Polyphosphates are linear polymers and ubiquitous metabolites. Bacterial polyphosphates
are long chains of hundreds of phosphate units. Here, we report that mouse survival of …
are long chains of hundreds of phosphate units. Here, we report that mouse survival of …
Serum microRNA profiles and pathways in hepatitis B-Associated hepatocellular carcinoma: a South African study
The incidence and mortality of hepatocellular carcinoma (HCC) in Sub-Saharan Africa is
projected to increase sharply by 2040 against a backdrop of limited diagnostic and …
projected to increase sharply by 2040 against a backdrop of limited diagnostic and …
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier
J Hauptmann, L Johann, F Marini, M Kitic… - Acta …, 2020 - Springer
The proinflammatory cytokine interleukin 1 (IL-1) is crucially involved in the pathogenesis of
multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis …
multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis …
Specific protein interactions between rice members of the GT43 and GT47 families form various central cores of putative xylan synthase complexes
Members of the glycosyltransferase (GT) 43 and GT47 families have been associated with
heteroxylan synthesis in both dicots and monocots and are thought to assemble into central …
heteroxylan synthesis in both dicots and monocots and are thought to assemble into central …
RNAlysis: analyze your RNA sequencing data without writing a single line of code
G Teichman, D Cohen, O Ganon, N Dunsky, S Shani… - BMC biology, 2023 - Springer
Background Among the major challenges in next-generation sequencing experiments are
exploratory data analysis, interpreting trends, identifying potential targets/candidates, and …
exploratory data analysis, interpreting trends, identifying potential targets/candidates, and …
GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data
F Marini, A Ludt, J Linke, K Strauch - BMC bioinformatics, 2021 - Springer
Background The interpretation of results from transcriptome profiling experiments via RNA
sequencing (RNA-seq) can be a complex task, where the essential information is distributed …
sequencing (RNA-seq) can be a complex task, where the essential information is distributed …
Interactive and Reproducible Workflows for Exploring and Modeling RNA‐seq Data with pcaExplorer, Ideal, and GeneTonic
The generation and interpretation of results from transcriptome profiling experiments via
RNA sequencing (RNA‐seq) can be a complex task. While raw data quality control …
RNA sequencing (RNA‐seq) can be a complex task. While raw data quality control …
Assessing male reproductive toxicity of environmental pollutant di-ethylhexyl phthalate with network toxicology and molecular docking strategy
Y Hong, Y Wang, D Wang, Q Yuan, Z Yang… - Reproductive …, 2024 - Elsevier
Environmental pollutants, especially endocrine-disrupting chemicals (EDCs) like di-
ethylhexyl phthalate (DEHP), pose serious threats to human health, with DEHP widely …
ethylhexyl phthalate (DEHP), pose serious threats to human health, with DEHP widely …
TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation
F Marini, D Scherzinger… - Nucleic Acids Research, 2021 - academic.oup.com
Alternative polyadenylation (APA) profoundly expands the transcriptome complexity.
Perturbations of APA can disrupt biological processes, ultimately resulting in devastating …
Perturbations of APA can disrupt biological processes, ultimately resulting in devastating …