[HTML][HTML] Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle

Y Huang, JC Hsu, H Koo, DP Cormode - Theranostics, 2022 - ncbi.nlm.nih.gov
Ferumoxytol is an intravenous iron oxide nanoparticle formulation that has been approved
by the US Food and Drug Administration (FDA) for treating anemia in patients with chronic …

MRI advancements in musculoskeletal clinical and research practice

DB Sneag, F Abel, HG Potter, J Fritz, MF Koff… - Radiology, 2023 - pubs.rsna.org
Over the past decades, MRI has become increasingly important for diagnosing and
longitudinally monitoring musculoskeletal disorders, with ongoing hardware and software …

In vivo imaging of nanoparticle-labeled CAR T cells

L Kiru, A Zlitni, AM Tousley, GN Dalton… - Proceedings of the …, 2022 - National Acad Sciences
Metastatic osteosarcoma has a poor prognosis with a 2-y, event-free survival rate of∼ 15 to
20%, highlighting the need for the advancement of efficacious therapeutics. Chimeric …

Biocompatible iron oxide nanoring-labeled mesenchymal stem cells: an innovative magnetothermal approach for cell tracking and targeted stroke therapy

H Liu, R Sun, L Wang, X Chen, G Li, Y Cheng, G Zhai… - ACS …, 2022 - ACS Publications
Labeling stem cells with magnetic nanoparticles is a promising technique for in vivo tracking
and magnetic targeting of transplanted stem cells, which is critical for improving the …

Applications of magnetic particle imaging in biomedicine: Advancements and prospects

X Yang, G Shao, Y Zhang, W Wang, Y Qi… - Frontiers in …, 2022 - frontiersin.org
Magnetic particle imaging (MPI) is a novel emerging noninvasive and radiation-free imaging
modality that can quantify superparamagnetic iron oxide nanoparticles tracers. The zero …

[HTML][HTML] Nanoparticle-based cell trackers for biomedical applications

JS Ni, Y Li, W Yue, B Liu, K Li - Theranostics, 2020 - ncbi.nlm.nih.gov
The continuous or real-time tracking of biological processes using biocompatible contrast
agents over a certain period of time is vital for precise diagnosis and treatment, such as …

The story of ferumoxytol: synthesis production, current clinical applications, and therapeutic potential

M Long, Y Li, H He, N Gu - Advanced Healthcare Materials, 2024 - Wiley Online Library
Ferumoxytol, approved by the US Food and Drug Administration in 2009, is one of the
intravenous iron oxide nanoparticles authorized for the treatment of iron deficiency in …

Unveiling the next generation of MRI contrast agents: Current insights and perspectives on ferumoxytol-enhanced MRI

G Si, Y Du, P Tang, G Ma, Z Jia, X Zhou… - National Science …, 2024 - academic.oup.com
Contrast-enhanced magnetic resonance imaging (CE-MRI) is a pivotal tool for global
disease diagnosis and management. Since its clinical availability in 2009, the off-label use …

[HTML][HTML] A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

P Karami, T Stampoultzis, Y Guo, DP Pioletti - Acta Biomaterialia, 2023 - Elsevier
The drive to develop cartilage implants for the treatment of major defects in the
musculoskeletal system has resulted in a major research thrust towards develo** …

Allogeneic mesenchymal stromal cells for cartilage regeneration: A review of in vitro evaluation, clinical experience, and translational opportunities

ED Aldrich, X Cui, CA Murphy, KS Lim… - Stem cells …, 2021 - academic.oup.com
The paracrine signaling, immunogenic properties and possible applications of
mesenchymal stromal cells (MSCs) for cartilage tissue engineering and regenerative …