Perspectives on sesquiterpene lactones in inflammation and cancer

I Merfort - Current drug targets, 2011 - ingentaconnect.com
Sesquiterpene lactones are a large group of secondary plant metabolites mostly known from
the Asteraceae family. They exert a broad variety of different biological activities. This review …

Development of anticancer agents from plant-derived sesquiterpene lactones

Y Ren, J Yu, A Douglas Kinghorn - Current medicinal chemistry, 2016 - ingentaconnect.com
Sesquiterpene lactones are of considerable interest due to their potent bioactivities,
including cancer cell cytotoxicity and antineoplastic efficacy in in vivo studies. Among these …

Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide

MRO Kreuger, S Grootjans, MW Biavatti… - Anti-cancer …, 2012 - journals.lww.com
Sesquiterpene lactones (SLs) constitute a large and diverse group of biologically active
plant compounds that possess anti-inflammatory and antitumor activity. The subclass …

[KIRJA][B] Autophagy: Cancer, other pathologies, inflammation, immunity, infection, and aging: Volume 12

MA Hayat - 2017 - books.google.com
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging,
Volume 12 discusses and details almost all aspects of the autophagy machinery in the …

Recent advances in α, β-unsaturated carbonyl compounds as mitochondrial toxins

M Hossain, U Das, JR Dimmock - European journal of medicinal chemistry, 2019 - Elsevier
Conjugated α, β-unsaturated ketones are very useful compounds associated with diverse
medicinal properties. This review outlines α, β-unsaturated ketones as candidate cytotoxic …

Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms

WL Lee, JY Huang, LF Shyur - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Accumulation of oxidized nucleic acids causes genomic instability leading to senescence,
apoptosis, and tumorigenesis. Phytoagents are known to reduce the risk of cancer …

Paclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress

T Hadzic, N Aykin-Burns, Y Zhu, MC Coleman… - Free Radical Biology …, 2010 - Elsevier
Cancer cells (relative to normal cells) demonstrate alterations in oxidative metabolism
characterized by increased steady-state levels of reactive oxygen species (ie, hydrogen …

Develo** phytocompounds from medicinal plants as immunomodulators

CC Wen, HM Chen, NS Yang - Advances in botanical research, 2012 - Elsevier
Imbalance or malfunction of the immune systems is associated with a range of chronic
diseases including autoimmune diseases, allergies, cancers and others. Various innate and …

[HTML][HTML] Current advancements of plant-derived agents for triple-negative breast cancer therapy through deregulating cancer cell functions and reprogramming tumor …

TN Wu, HM Chen, LF Shyur - International Journal of Molecular Sciences, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is defined based on the absence of estrogen,
progesterone, and human epidermal growth factor receptor 2 receptors. Currently …

Phytochemicals as Novel Therapeutics for Triple‐Negative Breast Cancer: A Comprehensive Review of Current Knowledge

ZA Bhutta, KC Choi - Phytotherapy Research, 2025 - Wiley Online Library
Triple‐negative breast cancer is a characteristic subtype of breast cancer that lacks the
estrogen receptor, human epidermal growth factor receptor 2, and progesterone receptor …