Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy

E Vacchelli, L Galluzzi, A Eggermont… - …, 2012 - Taylor & Francis
Toll-like receptors (TLRs) have first been characterized for their capacity to detect conserved
microbial components like lipopolysaccharide (LPS) and double-stranded RNA, resulting in …

Cochrane Review: Immunostimulants for preventing respiratory tract infection in children

BE Del‐Rio‐Navarro… - … ‐Based Child Health …, 2012 - Wiley Online Library
Background Acute respiratory tract infections (ARTIs) are a major cause of childhood
morbidity and mortality. Immunostimulants (IS) may reduce the incidence of ARTIs …

Toll‐like receptors: role in dermatological disease

A Hari, TL Flach, Y Shi… - Mediators of inflammation, 2010 - Wiley Online Library
Toll‐like receptors (TLRs) are a class of conserved receptors that recognize pathogen‐
associated molecular patterns (PAMPs) present in microbes. In humans, at least ten TLRs …

Highlights into historical and current immune interventions for cancer

K Cole, Z Al-Kadhimi, JE Talmadge - International immunopharmacology, 2023 - Elsevier
Immunotherapy is an additional pillar when combined with traditional standards of care such
as chemotherapy, radiotherapy, and surgery for cancer patients. It has revolutionized cancer …

[HTML][HTML] Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation

E Thurgar, S Barton, C Karner… - Health Technology …, 2016 - pmc.ncbi.nlm.nih.gov
BACKGROUND Typically occurring on the external genitalia, anogenital warts (AGWs) are
benign epithelial skin lesions caused by human papillomavirus infection. AGWs are usually …

Imiquimod: a review

AK Gupta, M Browne, R Bluhm - Journal of Cutaneous Medicine and …, 2002 - Springer
Background and Objective: Imiquimod (Aldara) is an immune response modifier used
primarily to treat anogenital warts. Imiquimod induces cytokines and enhances cell …

Human papillomavirus: burden of illness and treatment cost considerations

PA Fox, MY Tung - American journal of clinical dermatology, 2005 - Springer
The monetary and personal costs to society of human papillomavirus (HPV) infection are
enormous. In order to make a comparison of different treatment methods we reviewed the …

Imiquimod

RB Skinner - Dermatologic clinics, 2003 - derm.theclinics.com
Imiquimod, the first of a new class of compounds called immune response modifiers, is a
non-nucleoside, low modular weight, heterocyclic amine (imidizoquinolone) with the …

Therapy of external anogenital warts and molluscum contagiosum: a literature review

PT Ting, MT Dytoc - Dermatologic therapy, 2004 - Wiley Online Library
Anogenital warts and mollusca contagiosum are virally induced, benign skin tumors for
which there is no single preferable therapy. Treatments include physical and chemical …

Topically applied treatments for external genital warts in nonimmunocompromised patients: a systematic review and network meta‐analysis

JM Jung, CJ Jung, WJ Lee, CH Won… - British Journal of …, 2020 - academic.oup.com
Selecting a topical treatment from among the numerous topical agents for external genital
warts remains challenging without clear evidence. Our aim was to evaluate comparatively …