Vaccination is generally considered to be the most effective method of preventing infectious
diseases. All vaccinations work by presenting a foreign antigen to the immune system in …

In this paper, current prediction methods and algorithms for both T‐and B cell epitopes are
reviewed, and a comprehensive summary of epitope prediction software and databases …

We introduced previously an on-line resource, RANKPEP that uses position specific scoring
matrices (PSSMs) or profiles for the prediction of peptide-MHC class I (MHCI) binding as a …

Background It has been previously shown that combinatorial peptide libraries are a useful
tool to characterize the binding specificity of class I MHC molecules. Compared to other …

Peptides that bind to a given major histocompatibility complex (MHC) molecule share
sequence similarity. Therefore, a position specific scoring matrix (PSSM) or profile derived …

Background Protein antigens and their specific epitopes are formulation targets for epitope-
based vaccines. A number of prediction servers are available for identification of peptides …

Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules
by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a …

Background T-cells are key players in regulating a specific immune response. Activation of
cytotoxic T-cells requires recognition of specific peptides bound to Major Histocompatibility …

The sweetpotato whitefly Bemisia tabaci is a highly destructive agricultural and ornamental
crop pest. It damages host plants through both phloem feeding and vectoring plant …

Vaccine informatics is an emerging research area that focuses on development and
applications of bioinformatics methods that can be used to facilitate every aspect of the …