With the development of technology, more infants receive general anesthesia for surgery,
other interventions, or clinical examination at an early stage after birth. However, whether …

Tau protein is a microtubule-associated protein that is widely distributed in the central
nervous system and maintains and regulates neuronal morphology and function. Tau …

Alzheimer's Disease (AD) is the most common form of dementia in older adults and has a
devastating impact on the patient's quality of life, which creates a significant socio-economic …

Multiple sevoflurane exposure may result in cognitive deficits in neonatal animals. This study
attempted to investigate the potential mechanism of sevoflurane-induced neurotoxicity in …

Background Sevoflurane anaesthesia induces phosphorylation of the microtubule-
associated protein tau and cognitive impairment in neonatal, but not adult, mice. The …

Repeated neonatal exposures to sevoflurane induce long-term cognitive impairment that
has been reported to have sex-dependent differences. Exercise promotes learning and …

Neurodegenerative disease refers to a group of disorders that predominantly damage the
neurons in the brain. Despite significant progress in the knowledge of neurodegenerative …

General anesthetics depress excitatory and/or enhance inhibitory synaptic transmission
principally by modulating the function of glutamatergic or GABAergic synapses, respectively …

Postoperative cognitive dysfunction (POCD) is a frequent neurological complication
encountered during the perioperative period with unclear mechanisms and no effective …

Recent studies have highlighted the importance of vitamin K2 (VK2) in human health.
However, there have been no clinical studies investigating the role of VK2 in the prevention …