Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Reperfusion is a pre-requisite to salvaging viable myocardium, following an acute
myocardial infarction. Reperfusion of ischaemic myocardium, however, is not without risk, as …

Following an acute myocardial infarction (AMI), early coronary artery reperfusion remains
the most effective means of limiting the eventual infarct size. The resultant left ventricular …

Many changes occur during reperfusion of the myocardium after ischemic damage. Necrosis
and apoptosis appear to be ongoing during ischemia, while apoptosis is boosted by the …

Mammalian cardiomyocytes have limited proliferation potential, and acutely injured
mammalian hearts do not regenerate adequately. Instead, injured myocardium develops …

Ischemia-reperfusion (I/R) injury associated with liver transplantation remains a serious
complication in clinical practice, in spite of several attempts to solve the problem. The …

Abstract Fibroblast growth factor-2 (FGF-2) is a potent regulator of many cellular functions
and phenomena, including cell proliferation, differentiation, survival, adhesion, migration …

A hypercaloric diet combined with a sedentary lifestyle is a major risk factor for the
development of insulin resistance, type 2 diabetes mellitus (T2DM) and associated …

Fibronectin type III domain-containing (FNDC) proteins play critical roles in cellular
homeostasis and cardiac injury, and our recent findings define FNDC5 as a promising …

Fibroblast growth factor‐1 (FGF‐1) is a well characterized growth factor among the 22
members of the FGF superfamily in humans. It binds to all the four known FGF receptors and …