Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

PCL-PEG copolymer based injectable thermosensitive hydrogels

MR Dethe, A Prabakaran, H Ahmed, M Agrawal… - Journal of Controlled …, 2022 - Elsevier
A number of stimuli-responsive-based hydrogels has been widely explored in biomedical
applications in the last few decades because of their excellent biodegradability and …

Self-promoted electroactive biomimetic mineralized scaffolds for bacteria-infected bone regeneration

Z Li, D He, B Guo, Z Wang, H Yu, Y Wang, S **… - Nature …, 2023 - nature.com
Infected bone defects are a major challenge in orthopedic treatment. Native bone tissue
possesses an endogenous electroactive interface that induces stem cell differentiation and …

Bone regeneration strategies: Engineered scaffolds, bioactive molecules and stem cells current stage and future perspectives

A Ho-Shui-Ling, J Bolander, LE Rustom, AW Johnson… - Biomaterials, 2018 - Elsevier
Bone fractures are the most common traumatic injuries in humans. The repair of bone
fractures is a regenerative process that recapitulates many of the biological events of …

Polymers for 3D printing and customized additive manufacturing

SC Ligon, R Liska, J Stampfl, M Gurr… - Chemical …, 2017 - ACS Publications
Additive manufacturing (AM) alias 3D printing translates computer-aided design (CAD)
virtual 3D models into physical objects. By digital slicing of CAD, 3D scan, or tomography …

[HTML][HTML] Bone grafts and biomaterials substitutes for bone defect repair: A review

W Wang, KWK Yeung - Bioactive materials, 2017 - Elsevier
Bone grafts have been predominated used to treat bone defects, delayed union or non-
union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency …

The concept of scaffold-guided bone regeneration for the treatment of long bone defects: current clinical application and future perspective

M Laubach, F Hildebrand, S Suresh, M Wagels… - Journal of functional …, 2023 - mdpi.com
The treatment of bone defects remains a challenging clinical problem with high
reintervention rates, morbidity, and resulting significant healthcare costs. Surgical …

Advances in additive manufacturing for bone tissue engineering scaffolds

APM Madrid, SM Vrech, MA Sanchez… - Materials Science and …, 2019 - Elsevier
This article reviews the current state of the art of additive manufacturing techniques for the
production of bone tissue engineering (BTE) scaffolds. The most well-known of these …

Size matters: defining critical in bone defect size!

EH Schemitsch - Journal of orthopaedic trauma, 2017 - journals.lww.com
Bone defects are common and are associated with a significant burden of disease. The
treatment of these injuries remains controversial, particularly those defects which are critical …

High-strength, porous additively manufactured implants with optimized mechanical osseointegration

CN Kelly, T Wang, J Crowley, D Wills, MH Pelletier… - Biomaterials, 2021 - Elsevier
Optimization of porous titanium alloy scaffolds designed for orthopedic implants requires
balancing mechanical properties and osseointegrative performance. The tradeoff between …