The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications
Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor
immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and …
immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and …
Natural killer cells in antiviral immunity
Natural killer (NK) cells play an important role in innate immune responses to viral infections.
Here, we review recent insights into the role of NK cells in viral infections, with particular …
Here, we review recent insights into the role of NK cells in viral infections, with particular …
Designing cancer immunotherapies that engage T cells and NK cells
O Kyrysyuk, KW Wucherpfennig - Annual review of immunology, 2023 - annualreviews.org
T cells and natural killer (NK) cells have complementary roles in tumor immunity, and dual T
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …
NK cells and solid tumors: therapeutic potential and persisting obstacles
Natural killer (NK) cells, which are innate lymphocytes endowed with potent cytotoxic
activity, have recently attracted attention as potential anticancer therapeutics. While NK cells …
activity, have recently attracted attention as potential anticancer therapeutics. While NK cells …
Human NK cells: surface receptors, inhibitory checkpoints, and translational applications
NK cells play important roles in innate defenses against viruses and in the control of tumor
growth and metastasis. The regulation/induction of NK cell function is mediated by an array …
growth and metastasis. The regulation/induction of NK cell function is mediated by an array …
The role of natural killer cells in autoimmune diseases
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …
lymphoid progenitors, were discovered in early 1970's. They are members of innate …
CAR-T and CAR-NK as cellular cancer immunotherapy for solid tumors
In the past decade, chimeric antigen receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach for combating cancers, demonstrating remarkable …
promising immunotherapeutic approach for combating cancers, demonstrating remarkable …
Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies
4-1BB (CD137, tumor necrosis factor receptor superfamily 9) is an inducible costimulatory
receptor expressed on activated T and natural killer (NK) cells. 4-1BB ligation on T cells …
receptor expressed on activated T and natural killer (NK) cells. 4-1BB ligation on T cells …
[HTML][HTML] NK cells and ILCs in tumor immunotherapy
Cells of the innate immunity play an important role in tumor immunotherapy. Thus, NK cells
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …
Potential strategies overcoming the temozolomide resistance for glioblastoma
S Jiapaer, T Furuta, S Tanaka, T Kitabayashi… - Neurologia medico …, 2018 - jstage.jst.go.jp
Glioblastoma (GBM) is a highly malignant type of primary brain tumor with a high mortality
rate. Although the current standard therapy consists of surgery followed by radiation and …
rate. Although the current standard therapy consists of surgery followed by radiation and …