Abstract The use of Translocator Protein 18 kDa (TSPO) as a clinical neuroimaging
biomarker of brain injury and neuroinflammation has increased exponentially in the last …

Animal models of epilepsy and seizures, mostly involving mice and rats, are used to
understand the pathophysiology of the different forms of epilepsy and their comorbidities, to …

Fluorine-18 labelled N, N-diethyl-2-(2-[4-(2-fluoroethoxy) phenyl]-5, 7-dimethylpyrazolo [1, 5-
α] pyrimidine-3-yl) acetamide ([18F] DPA-714) binds to the 18-kDa translocator protein …

Background Magnetic resonance imaging (MRI)-guided pulsed focused ultrasound
combined with the infusion of microbubbles (pFUS+ MB) induces transient blood-brain …

Objective The role of neuroinflammation in mesial temporal lobe epilepsy (MTLE), and how
it relates to drug resistance, remains unclear. Expression levels of the inflammatory enzymes …

Neuroinflammation is thought to play a pivotal role in many diseases affecting the brain,
including Alzheimer's disease, multiple sclerosis and stroke. Neuroinflammation is …

Background Traumatic brain injury (TBI) is a major cause of death and disability.
Neuroinflammation contributes to acute damage after TBI and modulates long-term …

Introduction: In the epilepsy therapeutic arena, there is urgent need for develo** novel
antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the …

Stroke is the most common cause of death and disability from neurologic disease in
humans. Activation of microglia and matrix metalloproteinases (MMPs) is involved in …

Hybrid positron emission tomography/magnetic resonance imaging (PET/MR) systems are
now more and more available for clinical use. PET/MR combines the unique features of MR …