Berberine (BBR) is an isoquinoline plant alkaloid endowed with several pharmacological
activities, including anti-microbial, glucose-and cholesterol-lowering, anti-tumoral and …

In India, Ayurveda has made a major contribution to the drug discovery process with new
means of identifying active compounds. Recent advancement in bioavailability …

Many new chemical entities are discovered with high therapeutic potential, however, many
of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility …

Highlights•The nanostructured lipid carriers formula of berberine enhance its
efficiency.•Berberine-loaded nanostructured lipid carriers lessen warm hepatic …

The occurrence of efflux mechanisms via Permeability-glycoprotein (P-gp) recognized as an
important physiological process impedes drug entry or transport across membranes into …

Berberine (BBR) is an important natural product with poor gastrointestinal behavior includes
low permeability, P-glycoprotein efflux, and mass elimination in the intestine. The aim of this …

A drug design strategy with reduced side effects and economic feasibility is desirable for
fatal diseases. Increasing the bioavailability of a drug using a bioenhancer is a smart …

Apicomplexan parasites, especially Eimeria sp., are the main intestinal murine pathogens,
that lead to severe injuries to farm and domestic animals. Many anticoccidial drugs are …

Background: The objective of the present study was to evaluate the efficacy of a simple,
versatile and cost-effective immunosuppression protocol, using cyclosporine, ketoconazole …

The objective of this study was to understand the influence of membrane fouling on the
penetration of pharmaceutically active compounds (PhACs) in traditional Chinese medicine …