m6A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1

H Guo, B Wang, K Xu, L Nie, Y Fu, Z Wang… - Frontiers in …, 2020 - frontiersin.org
N6-methyladenosine (m6A) modification is the most abundant modification on eukaryotic
RNA. In recent years, lots of studies have reported that m6A modification and m6A RNA …

FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13

S Liu, M Huang, Z Chen, J Chen, Q Chao, X Yin… - Experimental cell …, 2020 - Elsevier
FTO, a demethylase for N 6-methyladenosine (m 6 A) modification, has been implicated in
multiple tumors. However, its roles in esophageal squamous cell carcinoma (ESCC) remain …

[HTML][HTML] NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway

J Xu, T Chen, L Liao, T Chen, Q Li, J Xu… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Esophageal squamous cell carcinoma (ESCC) causes aggressive and lethal malignancies
with extremely poor prognoses, and accounts for about 90% of cases of esophageal cancer …

BRCA1-associated protein is a potential prognostic biomarker and is correlated with immune infiltration in liver hepatocellular carcinoma: a pan-cancer analysis

Q Ju, X Li, H Zhang, Y Zhao - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
Background BRCA1-associated protein (BRAP) is a critical gene that regulates inflammation-
related signaling pathway and affects patients' prognosis in esophageal squamous cell …

Computational identification of preneoplastic cells displaying high stemness and risk of cancer progression

T Liu, X Zhao, Y Lin, Q Luo, S Zhang, Y **, Y Chen… - Cancer Research, 2022 - AACR
Evidence points toward the differentiation state of cells as a marker of cancer risk and
progression. Measuring the differentiation state of single cells in a preneoplastic population …

Systematic functional interrogation of genes in GWAS loci identified ATF1 as a key driver in colorectal cancer modulated by a promoter-enhancer interaction

J Tian, J Chang, J Gong, J Lou, M Fu, J Li, J Ke… - The American Journal of …, 2019 - cell.com
Genome-wide association studies (GWASs) have identified approximately 100 colorectal
cancer (CRC) risk loci. However, the causal genes in these loci have not been …

The CoV-Y domain of SARS-CoV-2 Nsp3 interacts with BRAP to stimulate NF-κB signaling and induce host inflammatory responses

K Wang, X Ni, X Deng, J Nan, Y Ma-Lauer… - International Journal of …, 2024 - Elsevier
Abstract Non-structural protein 3 (Nsp3) is the largest protein encoded by the coronavirus
(CoV) genome. It consists of multiple domains that perform critical functions during the viral …

CstF64-Induced Shortening of the BID 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with ZFP36L2

A Lin, P Ji, X Niu, X Zhao, Y Chen, W Liu, Y Liu, W Fan… - Cancer Research, 2021 - AACR
The majority of human genes have multiple polyadenylation sites, which are differentially
used through the process of alternative polyadenylation (APA). Dysregulation of APA …

BRCA1-associated protein inhibits glioma cell proliferation and migration and glioma stem cell self-renewal via the TGF-β/PI3K/AKT/mTOR signalling pathway

B Wang, C Cao, X Liu, X He, H Zhuang, D Wang… - Cellular Oncology, 2020 - Springer
Purpose BRCA1-associated protein (BRAP) was first identified by its ability to bind to the
nuclear localization signalling motif of BRCA1 and other proteins. Subsequently, human …

LncRNA miR205HG hinders HNRNPA0 translation: anti‐oncogenic effects in esophageal carcinoma

X Dong, X Chen, D Lu, D Diao, X Liu, S Mai… - Molecular …, 2022 - Wiley Online Library
Esophageal carcinoma (ESCA) affects 4 450 000 people and causes approximately 400
000 deaths annually worldwide, making it the sixth most lethal and eighth most common …